20297-37-4

• 常用中文名：1-甲基吡咯烷-2-甲腈
• 常用英文名：1-Methyl-2-pyrrolidinecarbonitrile
• CAS号：20297-37-4
• 分子式：C₆H₁₀N₂
• 分子量：110.15700
• 发布时间：2016-11-17 12:36:58
• 更新时间：2025-09-10 10:29:23

名称

• 中文名: 1-甲基吡咯烷-2-甲腈
• 英文名: 1-Methyl-2-pyrrolidinecarbonitrile
• 中文别名: 维格列汀杂质 8对照品; 特立氟胺相关杂质; 维达列汀杂质14; 维格列汀腈类杂质; 维达列汀杂质59; 1-甲基吡咯烷-2-氰基
• 英文别名: RAC 1-METHYL-PYRROLIDINE-2-carbonitrile; Vildagliptin impurities13; Vildagliptin carbonitrile Impurity; 2-Pyrrolidinecbonitrile, 1-methyl; 1-methyl-2-cyanopyrrolidine; N-Methyl-2-cyano-pyrrolidin; N-methyl-2-cyanopyrrolidine; Vildagliptin Impurity 14; rac 1-Methyl-pyrrolidine-2-cbonit; N-Methyl-pyrrolidin-2-nitril; 2,4,6-trinitrophenol-1-methylpyrrolidine(1:1); N-methylpyrrolidinium picrate; 1-methylpyrrolidine-2-carbonitrile; 1-Methyl-pyrrolidin,Picrat; 1-METHYL-PYRROLIDINE-2-carbonitrile; 1-methyl-pyrrolidine,picrate; 1-methyl-2-pyrrolidinecbonitrile; 1-Methyl-2-cyano-pyrrolidin

物化性质

• 密度: 1g/cm3
• 沸点: 188.792ºC at 760 mmHg
• 分子式: C₆H₁₀N₂
• 分子量: 110.15700
• 闪点: 68.906ºC
• 精确质量: 110.08400
• PSA: 27.03000
• LogP: 0.54208
• 蒸汽压: 0.589mmHg at 25°C
• 折射率: 1.485

合成路线

120-94-5 143-33-9 ~% 29134-29-0 20297-37-4

文献：Chen; Hortmann; Marzabadi Journal of the American Chemical Society, 1988 , vol. 110, # 14 p. 4829 - 4831

120-94-5 84-58-2 ~49% 20297-37-4

文献：Sundberg, Richard J.; Theret, Marie-Helene; Wright, Lorna Organic Preparations and Procedures International, 1994 , vol. 26, # 3 p. 386 - 389

120-94-5 151-50-8 ~24% 29134-29-0 872-50-4 详细

文献：Beckwith, Athelstan L. J.; Eichinger, Peter H.; Mooney, Brett A.; Prager, Rolf H. Australian Journal of Chemistry, 1983 , vol. 36, # 4 p. 719 - 739

120-94-5 ~24% 29134-29-0 872-50-4 20297-37-4 详细

文献：Beckwith, Athelstan L. J.; Eichinger, Peter H.; Mooney, Brett A.; Prager, Rolf H. Australian Journal of Chemistry, 1983 , vol. 36, # 4 p. 719 - 739

872-50-4 151-50-8 ~% 20297-37-4

文献：Langenskioeld, Tord; Lounasmaa, Mauri Heterocycles, 1983 , vol. 20, # 4 p. 671 - 675

上下游产品

上游产品  5
120-94-5 143-33-9 84-58-2 151-50-8
872-50-4
下游产品  1
67257-68-5