17615-73-5

• 常用中文名：2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺
• 常用英文名：5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide
• CAS号：17615-73-5
• 分子式：C₁₂H₁₃N₃O₄S₂
• 分子量：327.37900
• 发布时间：2019-01-17 20:24:08
• 更新时间：2024-01-03 19:43:24

名称

• 中文名: 2-(4-氨基苯磺酰基)-5-氨基苯磺酰胺
• 英文名: 5-amino-2-(4-aminophenyl)sulfonylbenzenesulfonamide
• 英文别名: Sulfamoyldapsone; 5-Amino-2-sulfanilyl-benzolsulfonsaeure-amid; Metanilamide,6-sulfanilyl; 6-(p-Anilinosulfonyl)metanilamide; 5-Amino-2-(4-amino-phenylsulfon)-benzolsulfonamid-(1); SDDS; 5-amino-2-[(4-aminophenyl)sulfonyl]benzenesulfonamide; 2-Sulfamonyl-4,4'-diaminophenylsulfone; 2-Sulfamonyl-4,4'-diaminodiphenyl-sulfone; 5-amino-2-sulfanilyl-benzenesulfonic acid amide

物化性质

• 密度: 1.549g/cm3
• 沸点: 686.1ºC at 760mmHg
• 分子式: C₁₂H₁₃N₃O₄S₂
• 分子量: 327.37900
• 闪点: 368.7ºC
• 精确质量: 327.03500
• PSA: 163.10000
• LogP: 4.35550
• 蒸汽压: 1.12E-18mmHg at 25°C
• 折射率: 1.681
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OY2230000 CHEMICAL NAME : Metanilamide, 6-sulfanilyl- CAS REGISTRY NUMBER : 17615-73-5 BEILSTEIN REFERENCE NO. : 3435880 LAST UPDATED : 199612 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C12-H13-N3-O4-S2 MOLECULAR WEIGHT : 327.40 WISWESSER LINE NOTATION : ZSWR CZ FSWR DZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - other changes REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >6 gm/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes Blood - pigmented or nucleated red blood cells Blood - changes in leukocyte (WBC) count REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5150 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Skin and Appendages - hair REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Mammal - pig DOSE/DURATION : >213 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 2,184,1968 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 24 gm/kg SEX/DURATION : female 9-14 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1800 mg/kg SEX/DURATION : female 9-14 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 120 mg/kg SEX/DURATION : female 9-14 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 9,695,1975

安全

• 海关编码: 2935009090

上下游产品

上游产品  6
24573-60-2 25006-65-9 946-94-1 100-00-5
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80-80-8

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%