188112-49-4

• 常用中文名：3,5-二甲基-4-三氟甲烷磺酰氧基苯甲醛
• 常用英文名：(4-formyl-2,6-dimethylphenyl) trifluoromethanesulfonate
• CAS号：188112-49-4
• 分子式：C₁₀H₉F₃O₄S
• 分子量：282.23600
• 发布时间：2018-12-05 16:54:03
• 更新时间：2024-01-09 16:29:48

名称

• 中文名: 3,5-二甲基-4-三氟甲烷磺酰氧基苯甲醛
• 英文名: (4-formyl-2,6-dimethylphenyl) trifluoromethanesulfonate
• 英文别名: 3,5-dimethyl-4-trifluoromethanesulfonyloxybenzaldehyde; Methanesulfonic acid,trifluoro-,4-formyl-2,6-dimethylphenyl ester; trifluoro-methanesulfonic acid 4-formyl-2,6-dimethyl-phenyl ester

物化性质

• 分子式: C₁₀H₉F₃O₄S
• 分子量: 282.23600
• 精确质量: 282.01700
• PSA: 68.82000
• LogP: 3.42510

合成路线

358-23-6 2233-18-3 ~56% 188112-49-4

文献：Bolli, Martin H.; Velker, Joerg; Mueller, Claus; Mathys, Boris; Birker, Magdalena; Bravo, Roberto; Bur, Daniel; De Kanter, Ruben; Hess, Patrick; Kohl, Christopher; Lehmann, David; Meyer, Solange; Nayler, Oliver; Rey, Markus; Scherz, Michael; Steiner, Beat Journal of Medicinal Chemistry, 2014 , vol. 57, # 1 p. 78 - 97

37595-74-7 4397-14-2 ~% 188112-49-4

文献：MERCK SHARP and DOHME CORP.; DUFFY, Joseph, L.; BAO, Jianming; ONDEYKA, Debra, L.; TYAGARAJAN, Sriram; SHAO, Patrick; YE, Feng; KATIPALLY, Revathi; FINKE, Paul, E.; ZANG, Yi; PLOTKIN, Michael, A.; ROMERO, F. Anthony; MONINGKA, Remond; HUSSAIN, Zahid Patent: WO2011/146324 A1, 2011 ; Location in patent: Page/Page column 76; 77 ; WO 2011/146324 A1

2233-18-3 1025373-45-8 ~% 188112-49-4

文献：Actelion Pharmaceuticals Ltd. Patent: EP1863475 B1, 2011 ;