188200-05-7

• 常用中文名：(S)-1-叔丁基 2-甲基 5-羟基吡咯烷-1,2-二羧酸
• 常用英文名：(2S)-1-TERT-BUTYL 2-METHYL 5-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE
• CAS号：188200-05-7
• 分子式：C₁₁H₁₉NO₅
• 分子量：245.27200
• 发布时间：2018-12-28 11:36:18
• 更新时间：2026-07-14 10:29:19

名称

• 中文名: (S)-1-叔丁基 2-甲基 5-羟基吡咯烷-1,2-二羧酸
• 英文名: 1-O-tert-butyl 2-O-methyl (2S)-5-hydroxypyrrolidine-1,2-dicarboxylate
• 中文别名: 1-(叔丁基)-2-甲基(2S)-5-羟基吡咯烷-1,2-二羧酸酯; (2S)-1-BOC-5-羟基吡咯烷-2-甲酸甲酯; N-BOC-5-羟基-L-焦谷氨酸甲酯
• 英文别名: (S)-1-tert-Butyl 2-methyl 5-hydroxypyrrolidine-1,2-dicboxylate; RMA-532; (2S)-1-tert-Butyl 2-methyl 5-hydroxypyrrolidine-1,2-dicboxylate; 1-O-tert-butyl 2-O-methyl (2S)-5-hydroxypyrrolidine-1,2-dicboxylate; Methyl (2S)-1-Boc-5-hydroxypyrrolidine-2-cboxylate; 1-(tert-Butyl) 2-methyl (2S)-5-hydroxypyrrolidine-1,2-dicboxylate; 5-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester; 1,2-Pyrrolidinedicboxylic acid, 5-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S); Boc-5-hydroxyproline methyl ester

物化性质

• 分子式: C₁₁H₁₉NO₅
• 分子量: 245.27200
• 精确质量: 245.12600
• PSA: 76.07000
• LogP: 0.81520

安全

• 海关编码: 2933990090

合成路线

15761-39-4 ~% 188200-05-7

文献：Saladino, Raffaele; Mezzetti, Maurizio; Mincione, Enrico; Torrini, Ines; Paradisi, Mario Paglialunga; Mastropietro, Gaia Journal of Organic Chemistry, 1999 , vol. 64, # 23 p. 8468 - 8474

24424-99-5 ~% 188200-05-7

文献：Clive, Derrick L. J.; Yeh, Vince S. C. Tetrahedron Letters, 1998 , vol. 39, # 27 p. 4789 - 4792

108963-96-8 ~10% 188200-05-7

文献：Collado, Ivan; Ezquerra, Jesus; Vaquero, Juan Jose; Pedregal, Concepcion Tetrahedron Letters, 1994 , vol. 35, # 43 p. 8037 - 8040

59936-29-7 ~88% 188200-05-7

文献：Saladino, Raffaele; Mezzetti, Maurizio; Mincione, Enrico; Torrini, Ines; Paradisi, Mario Paglialunga; Mastropietro, Gaia Journal of Organic Chemistry, 1999 , vol. 64, # 23 p. 8468 - 8474

4931-66-2 ~% 188200-05-7

文献：Aggarwal, Varinder K.; Astle, Christopher J.; Iding, Hans; Wirz, Beat; Rogers-Evans, Mark Tetrahedron Letters, 2005 , vol. 46, # 6 p. 945 - 947

13574-13-5 ~% 188200-05-7

文献：Tamura, Susan Y.; Goldman, Erick A.; Brunck, Terence K.; Ripka, William C.; Semple, J. Edward Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 3 p. 331 - 336

72086-72-7 ~% 188200-05-7

文献：Tamura, Susan Y.; Goldman, Erick A.; Brunck, Terence K.; Ripka, William C.; Semple, J. Edward Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 3 p. 331 - 336

59279-58-2 ~% 188200-05-7

文献：Tamura, Susan Y.; Goldman, Erick A.; Brunck, Terence K.; Ripka, William C.; Semple, J. Edward Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 3 p. 331 - 336

98-79-3 ~% 188200-05-7

文献：Aggarwal, Varinder K.; Astle, Christopher J.; Iding, Hans; Wirz, Beat; Rogers-Evans, Mark Tetrahedron Letters, 2005 , vol. 46, # 6 p. 945 - 947

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%