194022-51-0

194022-51-0结构式

中文名	乙酰基-缬氨酰-天冬氨酰-缬氨酰-丙氨酰-天冬氨醛
英文名	(3S)-3-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-carboxy-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid
中文别名	BIOTIN标记的半胱胺酸蛋白酶-2抗体半胱胺酸蛋白酶-2重组兔单抗 IRDYE 800CW标记的半胱胺酸蛋白酶-2抗体 AP标记的半胱胺酸蛋白酶-2抗体 HRP标记的半胱胺酸蛋白酶-2抗体
英文别名	AC-VAL-ASP-VAL-ALA-ASP-H (ALDEHYDE) AC-VAL-ASP-ALA-ASP-CHO Ac-VDVAD-CHO (3S)-3-[[(2S)-2-acetamido-3-methylbutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-cboxy-3-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid CASPASE 2 INHIBITOR CASPASE INHIBITOR VIII ACETYL-L-VALYL-L-ASPTYL-L-VALYL-L-ALANYL-L-ASPT-1-AL 2h65 AC-VAL-ASP-VAL-ASP-CHO AC-VAL-ASP-VAL-ALA-ASP-ALDEHYDE CASPASE-2 INHIBITOR (ALDEHYDE) N-Acetyl-Val-Asp-Val-Ala-Asp-CHO N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide N-ACETYL-VAL-ASP-VAL-ALA-ASP-CHO AC-VAL-ASP-VAL-ALA-ASP-ALDEHYDE (PSEUDO ACID) AC-VAL-ASP-VAL-ALA-ASP-CHO L-Alaninamide, N-acetyl-L-valyl-L-α-asptyl-L-valyl-N-[(1S)-2-cboxy-1-formylethyl] AC-VDVAD-ALDEHYDE Acetyl-valyl-asptyl-valyl-alanyl-asptal AC-VAVAD-CHO AC-VDVAD-CHO

描述	Ac-VDVAD-CHO 是一种 caspase-2/3 抑制剂 (IC50: 46 and 15 nM)。
相关类别	研究领域 >> 其他信号通路 >> 细胞周期/DNA损伤 >> 酪蛋白激酶信号通路 >> 干细胞及 Wnt 通路 >> 酪蛋白激酶
靶点	caspase-2/3[1]
参考文献	[1]. Maillard MC, et al. Exploiting differences in caspase-2 and -3 S₂ subsites for selectivity: structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg Med Chem. 2011 Oct 1;19(19):5833-51.

WGK德国	3