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78299-53-3

78299-53-3结构式
78299-53-3结构式
  • 常用中文名:硫克司特
  • 常用英文名:Tiacrilast
  • CAS号:78299-53-3
  • 分子式:C12H10N2O3S
  • 分子量:262.28400
  • 发布时间:2018-05-17 08:00:00
  • 更新时间:2024-01-18 11:10:13

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中文名 硫克司特
英文名 (E)-3-(6-methylsulfanyl-4-oxoquinazolin-3-yl)prop-2-enoic acid
英文别名 TIACRILAST
Ro-22-3747
密度 1.38g/cm3
沸点 499.3ºC at 760 mmHg
分子式 C12H10N2O3S
分子量 262.28400
闪点 255.8ºC
精确质量 262.04100
PSA 97.49000
LogP 1.67370
折射率 1.658

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UD3550000
CHEMICAL NAME :
2-Propenoic acid, 3-(6-(methylthio)-4-oxo-3(4H)-quinazolinyl)-, (E)-
CAS REGISTRY NUMBER :
78299-53-3
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C12-H10-N2-O3-S
MOLECULAR WEIGHT :
262.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 10,131,1985

海关编码 2933990090
海关编码 2933990090
中文概述 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%