94633-25-7

• 常用中文名：2-(2,2,2-三氟乙酰基)琥珀酸二乙酯
• 常用英文名：diethyl 2-(2,2,2-trifluoroacetyl)succinate
• CAS号：94633-25-7
• 分子式：C₁₀H₁₃F₃O₅
• 分子量：270.20200
• 发布时间：2016-01-20 12:43:08
• 更新时间：2025-09-22 16:52:26

名称

• 中文名: 2-(2,2,2-三氟乙酰基)琥珀酸二乙酯
• 英文名: diethyl 2-(2,2,2-trifluoroacetyl)butanedioate
• 中文别名: 2-(2,2,2-三氟乙烷酰基)琥珀酸二乙酯
• 英文别名: ethyl 5,5,5-trifluoro-4-oxo-3-ethoxycarbonyl-pentanoate; 2-(2,2,2-trifluoroacetyl)succinic acid diethyl ester; DIETHYL 2-(2,2,2-TRIFLUOROACETYL)SUCCINATE(94-7)/PO22003128; trifluoroacetyl-2 succinate d'ethyle; ethyl 5,5,5-trifluoro-4-oxo-3-ethoxycbonyl-pentanoate; diethyl 2-trifluoroacetylsuccinate; Butanedioic acid, 2-(2,2,2-trifluoroacetyl)-, 1,4-diethyl ester; Butanedioic acid,(trifluoroacetyl)-,diethyl ester; diethyl trifluoroacetylsuccinate; diethyl trifluoroacetosuccinate

物化性质

• 分子式: C₁₀H₁₃F₃O₅
• 分子量: 270.20200
• 精确质量: 270.07200
• PSA: 69.67000
• LogP: 1.25030

合成路线

383-63-1 123-25-1 ~77% 94633-25-7

文献：NOVARTIS AG Patent: WO2008/74752 A2, 2008 ; Location in patent: Page/Page column 33 ; WO 2008/074752 A2

105-36-2 372-31-6 ~53% 94633-25-7

文献：PONIARD PHARMACEUTICALS, INC. Patent: WO2009/139834 A1, 2009 ; Location in patent: Page/Page column 164 ;

105-39-5 372-31-6 ~79% 94633-25-7

文献：Blobaum, Anna L.; Uddin, Md. Jashim; Felts, Andrew S.; Crews, Brenda C.; Rouzer, Carol A.; Marnett, Lawrence J. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 5 p. 486 - 490

431-47-0 123-25-1 ~% 94633-25-7

文献：Wan, Wen; Hou, Jie; Jiang, Haizhen; Wang, Yangli; Zhu, Shizheng; Deng, Hongmei; Hao, Jian Tetrahedron, 2009 , vol. 65, # 21 p. 4212 - 4219