56703-34-5

• 常用中文名：3-(4-(羟甲基)苯基)丙酸
• 常用英文名：3-(4-(Hydroxymethyl)Phenyl)Propanoic Acid
• CAS号：56703-34-5
• 分子式：C₁₀H₁₂O₃
• 分子量：180.20000
• 发布时间：2018-09-12 19:45:29
• 更新时间：2024-01-06 06:40:58

名称

• 中文名: 3-[4-(羟基甲基)苯基]丙酸
• 英文名: 3-[4-(hydroxymethyl)phenyl]propanoic acid
• 英文别名: 4-Hydroxymethyl-hydrozimtsaeure; 4-hydroxymethyl-hydrocinnamic acid

物化性质

• 分子式: C₁₀H₁₂O₃
• 分子量: 180.20000
• 精确质量: 180.07900
• PSA: 57.53000
• LogP: 1.19610
• 储存条件: 室温

合成路线

23359-08-2 ~99% 56703-34-5

文献：ALMIRALL, S.A.; DRACONIS PHARMA, S.L.; LABORATORIOS DEL DR. ESTEVE, S.A.; AGUILAR, Nuria; FERNANDEZ, Joan, Carles; TERRICABRAS, Emma; CARCELLER GONZALEZ, Elena; SALAS SOLANA, Jordi Patent: WO2013/149997 A1, 2013 ; Location in patent: Page/Page column 46 ;

283153-64-0 ~97% 56703-34-5

文献：CHROMA THERAPEUTICS LTD. Patent: WO2008/40934 A1, 2008 ; Location in patent: Page/Page column 81-82 ; WO 2008/040934 A1

66885-68-5 ~% 56703-34-5

文献：Actelion Pharmaceuticals Ltd. Patent: EP1863475 B1, 2011 ;

56703-33-4 ~85% 56703-34-5

文献：Arshady, Reza; Atherton, Eric; Clive, Derek L. J.; Sheppard, Robert C. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 529 - 537

66885-68-5 ~% 1505-50-6 56703-34-5

文献：Westaway, Susan M.; Brown, Samantha L.; Fell, Stephen C. M.; Johnson, Christopher N.; MacPherson, David T.; Mitchell, Darren J.; Myatt, James W.; Stanway, Steven J.; Seal, Jon T.; Stemp, Geoffrey; Thompson, Mervyn; Lawless, Kirk; McKay, Fiona; Muir, Alison I.; Barford, Jonathan M.; Cluff, Chermaine; Mahmood, Sadhia R.; Matthews, Kim L.; Mohamed, Shiyam; Smith, Beverley; Stevens, Alexander J.; Bolton, Victoria J.; Jarvie, Emma M.; Sanger, Gareth J. Journal of Medicinal Chemistry, 2009 , vol. 52, # 4 p. 1180 - 1189

上下游产品

上游产品  4
23359-08-2 283153-64-0 66885-68-5 56703-33-4
下游产品  4
34961-64-3 81121-62-2 56703-35-6 38628-53-4