95-29-4

• 常用中文名：N,N-二异丙基-2-苯并噻唑次磺酰胺
• 常用英文名：N,N-diisopropylbenzothiazole-2-sulphenamide
• CAS号：95-29-4
• 分子式：C₁₃H₁₈N₂S₂
• 分子量：266.42500
• 发布时间：2018-12-25 19:57:46
• 更新时间：2024-01-03 02:43:33

• 本品为后效性促进剂。在天然橡胶中延迟作用比促进剂NOBS(N氧二亚乙基-2-苯并噻唑次磺酰胺)大，而且在硫化温度下硫化速度也较快。硫化平坦性宽，一般可采用较高的硫化温度（130～160℃）。通常用于制造轮胎、胶管、胶带、工业制品等。一般用量为0.4～1.5份，并配以2.5～0.5份的硫黄。

名称

• 中文名: N,N-二异丙基-2-苯并噻唑次磺酰胺
• 英文名: N-(1,3-benzothiazol-2-ylsulfanyl)-N-propan-2-ylpropan-2-amine
• 中文别名: N,N-二异丙基苯并噻唑-2-亚磺酰胺; 硫化促进剂DIBS
• 英文别名: N,N-di-isopropyl-benzothiazolesulphenamide; S-benzothiazol-2-yl-N,N-diisopropyl-thiohydroxylamine; N,N-diisopropylbenzothiazole-2-sulphenamide; N,N-Diisopropyl-2-benzothiazolesulfenamide; benzothiazole-2-sulfenic acid diisopropylamide; DIPAC; Benzothiazol-2-sulfensaeure-diisopropylamid; N,N-diisopropylbenzothiazole-2-sulfenamide; EINECS 202-407-0; DIPAK; DIBS; Dipac (accelerator); Meramid P; Santocure IPS; 2-Benzothiazolesulfenamide,N,N-bis(1-methylethyl)

物化性质

• 分子式: C₁₃H₁₈N₂S₂
• 分子量: 266.42500
• 精确质量: 266.09100
• PSA: 69.67000
• LogP: 4.42220
• 储存条件:

  本品采用内衬塑料袋，外用布袋包装。本品在室温下储存稳定，一般储存期自生产日起6个月。

• 分子结构:

  1、 摩尔折射率：79.87

  2、 摩尔体积（cm³/mol）：227.2

  3、 等张比容（90.2K）：603.9

  4、 表面张力（dyne/cm）：49.9

  5、 极化率（10-24cm3）：31.66

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:4

  4.可旋转化学键数量:4

  5.互变异构体数量:无

  6.拓扑分子极性表面积69.7

  7.重原子数量:17

  8.表面电荷:0

  9.复杂度:238

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1.性状：工业品为浅黄色粉末

  2相对密度：1.21～1.23

  3.熔点（℃）：55～60

  4.溶解性：溶于苯、丙酮、乙醚和甲醇，不溶于水。在室温下储存稳定。

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DL6330000 CHEMICAL NAME : 2-Benzothiazolesulfenamide, N,N-diisopropyl- CAS REGISTRY NUMBER : 95-29-4 BEILSTEIN REFERENCE NO. : 0177776 LAST UPDATED : 199712 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C13-H18-N2-S2 MOLECULAR WEIGHT : 266.45 WISWESSER LINE NOTATION : T56 BN DSJ CSO&NY1&1&Y1&1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5200 mg/kg TOXIC EFFECTS : Behavioral - ataxia Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3892 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(7),39,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0538647 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1820 mg/kg/17W-I TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 8(7),39,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7138 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 18 No. of Employees: 3940 (estimated) No. of Female Employees: 14 (estimated)

安全

• 海关编码: 2934999090

合成路线

149-30-4 ~81% 95-29-4

文献：MONSANTO EUROPE S.A. Patent: EP314663 A1, 1989 ;

149-30-4 2492-26-4 ~% 95-29-4

文献：US4719305 A1, ;

24948-81-0 149-30-4 ~% 95-29-4

文献：US4719305 A1, ;

149-30-4 108-18-9 ~75% 95-29-4

文献：Brownbridge, P.; Jowett, I. C. Phosphorus and Sulfur and the Related Elements, 1988 , vol. 35, p. 311 - 318

120-78-5 108-18-9 ~% 95-29-4

文献：Journal of Organic Chemistry, , vol. 43, p. 3223 - 3227

24948-81-0 2492-26-4 ~% 95-29-4

文献：US2776297 , ;

24948-81-0 120-78-5 108-18-9 ~% 95-29-4

文献：US2782202 , ;

上下游产品

上游产品  5
149-30-4 2492-26-4 24948-81-0 108-18-9
120-78-5
下游产品  0

制备

（1）氯代二异丙胺的制备将有效氯含量大于25%的次氯酸钠，在激烈搅拌下，连续滴加到装有二异丙胺的反应釜内,将反应温度控制在25℃以下。反应结束后，静置分去氢氧化钠废液，制得氯代二异丙胺。

（2）将甲醇投入反应釜，再加入氯代二异丙胺、2-二硫代二苯并噻唑（促进剂DM）及二异丙胺，开动搅拌使物料溶解，升温至65℃进行反应。反应完成后，反应产物经冷却、甩滤、水洗、干燥即得成品。过滤母液进行蒸馏回收甲醇及二异丙胺盐酸盐。

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%