487-48-9

• 常用中文名：醋水杨胺
• 常用英文名：Benzamide,N-acetyl-2-hydroxy
• CAS号：487-48-9
• 分子式：C₉H₉NO₃
• 分子量：179.17300
• 相关类别： 原料药 解热镇痛药 解热止痛药
• 发布时间：2018-08-04 16:21:47
• 更新时间：2026-07-31 07:59:37
• Salacetamide(N-乙酰水杨酰胺)是O-乙酰水杨酰胺的稳定异构体,是蛋白质组学研究的产物[1]。

名称

• 中文名: 醋水杨胺
• 英文名: n-acetylsalicylamide
• 中文别名: N-乙酰基-2-羟基苯甲酰胺; N-乙酰-2-羟基苯甲酰胺
• 英文别名: N-Acetyl-2-hydroxybenzamide; Acetsalicylamide; N-Acetylsaicylamide; n-acetyl-salicylamid; Rixamone; N-ethanoyl-2-hydroxy-benzamide; Labazyl; Salacetamid; thrisin; N-Acetyl-salicylamid; Actylamide; Acetsallicylamide; Nacemide; Ethrisin; N-Salicoyl-acetamid; n-acetyl-2-hydroxy-benzamid; Salacetamidum; Benzamide, N-acetyl-2-hydroxy; TOSLAB; Salicyl; Acetyl-salicyloyl-amin; acetyl-salicyloyl-amine; salacetamide; (4R,5S,6S)-3-[[(3S,5S)-5-[[(3-Cboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]ht-2-ene-2-cboxylic Acid SodiuM Salt; N-ACETYLSALICYLAMIDE //BP; 2-Hydroxy-N-acetylbenzamide; Arthrisin; N-ACETYLSALICYLAMIDE; Salicylamide, N-acetyl; NSC40153; NSC-40153; L-749

物化性质

• 密度: 1.263g/cm3
• 沸点: 375.4ºC at 760mmHg
• 熔点: 148°
• 分子式: C₉H₉NO₃
• 分子量: 179.17300
• 闪点: 180.9ºC
• 精确质量: 179.05800
• PSA: 66.40000
• LogP: 1.05940
• 蒸汽压: 3.6E-06mmHg at 25°C
• 折射率: 1.568

生物活性

• 描述: Salacetamide(N-乙酰水杨酰胺)是O-乙酰水杨酰胺的稳定异构体,是蛋白质组学研究的产物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. A.J.Gordon. Acetylsalicylamide o- to N-acetyl migration. Tetrahedron. 23(2). 1967:863-870.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VN6650000 CHEMICAL NAME : Salicylamide, N-acetyl- CAS REGISTRY NUMBER : 487-48-9 LAST UPDATED : 199709 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H9-N-O3 MOLECULAR WEIGHT : 179.19 WISWESSER LINE NOTATION : QR BVMV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,205,1947 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2440378

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