1977-08-8

• 常用中文名：2-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
• 常用英文名：2-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine
• CAS号：1977-08-8
• 分子式：C₁₈H₁₉ClN₄
• 分子量：326.82300
• 发布时间：2017-12-02 20:54:26
• 更新时间：2025-09-12 13:05:43

名称

• 英文名: 8-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine
• 英文别名: 2-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine; ISOCLOZAPINE; 5H-DIBENZO(b,e)(1,4)DIAZEPINE,2-CHLORO-11-(4-METHYL-1-PIPERAZINYL); 2-Chloro-11-(4-methyl-1-piperazinyl)-5H-benzo(b,e)(1,4)diazepine; 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine; 2-chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine

物化性质

• 分子式: C₁₈H₁₉ClN₄
• 分子量: 326.82300
• 精确质量: 326.13000
• PSA: 30.87000
• LogP: 3.17210
• 蒸汽压: 1.62E-09mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HP1700000 CHEMICAL NAME : 5H-Dibenzo(b,e)(1,4)diazepine, 2-chloro-11-(4-methyl-1-piperazinyl)- CAS REGISTRY NUMBER : 1977-08-8 BEILSTEIN REFERENCE NO. : 0763655 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H19-Cl-N4 MOLECULAR WEIGHT : 326.86 WISWESSER LINE NOTATION : T C676 BM INJ MG J- AT6N DNTJ D1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 15,841,1965