357262-90-9

• 常用中文名：4-苯甲酰基-2-甲基-1-[(7-氧化-1H-吡咯并[2,3-b]吡啶)氧代乙酰基]-哌嗪
• 常用英文名：4-benzoyl-2-methyl-1-[(7-oxido-1h-pyrrolo[2,3-b] pyridin-3-yl)oxoacetyl]-piperazine
• CAS号：357262-90-9
• 分子式：C₂₁H₂₀N₄O₄
• 分子量：392.408
• 发布时间：2018-12-27 08:56:48
• 更新时间：2024-01-13 17:47:28

名称

• 中文名: 4-苯甲酰基-2-甲基-1-[(7-氧化-1H-吡咯并[2,3-b]吡啶)氧代乙酰基]-哌嗪
• 英文名: 4-benzoyl-2-methyl-1-[(7-oxido-1h-pyrrolo[2,3-b] pyridin-3-yl)oxoacetyl]-piperazine
• 英文别名: 4(R)-3-(2-(4-BENZOYL-2-METHYLPIPERAZIN-1-YL)-2-OXOACETYL)-1H-PYRROLO[2,3-B]PYRIDINE 7-OXIDE; 4-Benzoyl-2-methyl-1-[(7-oxido-1H-pyrroli[2,3-b]pyridin-3-yl)oxoacetyl]-piperazine; (R)-4-Benzoyl-2-methyl-1-[3-(7-azaindole)oxoacetyl] piperazine; 4-benzoyl-2-(R)-methyl-1-[(7-oxido-1H-pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]piperazine; 1-(4-Benzoyl-2-methyl-1-piperazinyl)-2-(7-oxido-1H-pyrrolo[2,3-b]pyridin-3-yl)-1,2-ethanedione; 1,2-Ethanedione, 1-(4-benzoyl-2-methyl-1-piperazinyl)-2-(7-oxido-1H-pyrrolo[2,3-b]pyridin-3-yl)-

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 664.0±65.0 °C at 760 mmHg
• 分子式: C₂₁H₂₀N₄O₄
• 分子量: 392.408
• 闪点: 355.4±34.3 °C
• 精确质量: 392.148468
• PSA: 98.94000
• LogP: -2.24
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.687

合成路线

357262-60-3 ~89% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

93-58-3 ~% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

271-63-6 ~% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

75336-86-6 ~% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

357263-49-1 ~% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

357263-39-9 ~% 357262-90-9

文献：Wang, Tao; Zhang, Zhongxing; Wallace, Owen B.; Deshpande, Milind; Fang, Haiquan; Yang, Zheng; Zadjura, Lisa M.; Tweedie, Donald L.; Huang, Stella; Zhao, Fang; Ranadive, Sunanda; Robinson, Brett S.; Gong, Yi-Fei; Ricarrdi, Keith; Spicer, Timothy P.; Deminie, Carol; Rose, Ronald; Wang, Hwei-Gene Heidi; Blair, Wade S.; Shi, Pei-Yong; Lin, Pin-Fang; Colonno, Richard J.; Meanwell, Nicholas A. Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4236 - 4239

上下游产品

上游产品  6
357262-60-3 93-58-3 271-63-6 75336-86-6
357263-49-1 357263-39-9
下游产品  1
357263-13-9