17297-82-4

• 常用中文名：1-Piperazineethanol,4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-, hydrochloride (1:2)
• 常用英文名：1-Piperazineethanol,4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-, hydrochloride (1:2)
• CAS号：17297-82-4
• 分子式：C₂₀H₂₇ClN₄OS
• 分子量：406.97300
• 发布时间：2016-05-19 22:44:08
• 更新时间：2024-02-28 18:55:08

名称

• 英文名: Oxypendyl dihydrochloride
• 英文别名: perthipendyl,dihydrochloride; 2-[4-(3-benzo[b]pyrido[2,3-e][1,4]thiazin-10-yl-propyl)-piperazin-1-yl]-ethanol,dihydrochloride; Pervetral; 4-[3-(10H-pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]piperazine-1-ethanol dihydrochloride; 1-Piperazineethanol,4-[3-(10H-pyrido[3,2-B][1,4]benzothiazin-10-yl)propyl]-,dihydrochloride; oxypendyl,dihydrochloride; Pervetral dihydrochloride

物化性质

• 密度: 1.22g/cm3
• 沸点: 575.5ºC at 760mmHg
• 分子式: C₂₀H₂₇ClN₄OS
• 分子量: 406.97300
• 闪点: 301.8ºC
• 精确质量: 406.15900
• PSA: 68.14000
• LogP: 3.42710
• 蒸汽压: 4.39E-14mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL9450000 CHEMICAL NAME : 1-Piperazineethanol, 4-(3-(10H-pyrido(3,2-b)(1,4)benzothiazin-10-yl)propyl )-, dihydrochloride CAS REGISTRY NUMBER : 17297-82-4 LAST UPDATED : 199012 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H26-N4-O-S.2Cl-H MOLECULAR WEIGHT : 443.48 WISWESSER LINE NOTATION : T C666 BS DN INJ I3- AT6N DNTJ D2Q &GH 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1610 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 735 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 139 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,435,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 352 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,273,1972