50787-09-2

• 常用中文名：2-乙酰氨基-2-脱氧-3-O-(BETA-D-氟代半乳糖)-D-吡喃葡萄糖
• 常用英文名：2-ACETAMIDO-2-DEOXY-3-O-(BETA-D-GALACTOPYRANOSYL)-D-GLUCOPYRANOSE
• CAS号：50787-09-2
• 分子式：C₁₄H₂₅NO₁₁
• 分子量：383.34800
• 相关类别： 研究领域 内分泌
• 发布时间：2018-12-29 14:52:25
• 更新时间：2026-08-06 18:46:44
• 乳糖-N-二糖I(Galβ1-3GlcNAc)作为内源性代谢产物,是幽门螺杆菌α1,2-岩藻糖基转移酶的受体[1]。

名称

• 中文名: 2-乙酰氨基-2-脱氧-3-o-(beta-d-氟代半乳糖)-d-吡喃葡萄糖
• 英文名: 2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-D-glucopyranose
• 中文别名: 乳-N-乙糖; 2-乙酰氨基-2-脱氧-3-O- (Β-D-半乳糖吡喃基)-D-吡喃葡萄糖; 2-乙酰氨基-2-脱氧-3-O-(Β-D-吡喃半乳糖基)-D-吡喃葡萄糖; 乳糖-N-乙糖; N-((2R,3R,4R,5R)-4,5,6-三羟基-1-氧代-3-(((2R,3R,4S,5R,6R)-3,4,5-三羟基-6-(羟基甲基)四氢-2H-吡喃-2-基)氧基)己烷-2-基)乙酰胺; 乳糖-N-二糖 (Β1-3半乳糖-N-乙酰葡糖胺); 半乳糖β1-3-N-乙酰葡糖胺
• 英文别名: LACTO-N-BIOSE I; 2-Acetamido-2-deoxy-3-O-(2-D-galactopyranosyl)-D-glucopyranose; 2-acetamido-2-deoxy-3-O-B-D-*galactopyranosyl-D; β-D-Gal-D-GlcNAc, 2-Acetamido-2-deoxy-3-O-(β-D-galactopyranosyl)-D-glucopyranose; 2-Acetamido-2-deoxy-3-O-(b-D-galactopyranosyl)-D-glucopyranose; LACTO-N-BIOSE; Gal1-3GlcNAc; 2-ACETAMIDO-2-DEOXY-3-O-(β-D-GALACTOPYRANOSYL)-D-GLUCOPYRANOSE; GAL1-B-3GLCNAC; O-D-Galactopyranosyl-N-acetylglucosamine; LNB（Lacto-N-biose:Galβ1,3GlcNAc); D-Glucose, 2-(acetylamino)-2-deoxy-3-O-β-D-galactopyranosyl; N-[(3R,4R,5R,6R)-2,5-dihydroxy-6-(hydroxymethyl)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-oxan-3-yl]acetamide; Lacto-N-biose 1; N-((2R,3R,4R,5R)-4,5,6-Trihydroxy-1-oxo-3-(((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetamide; galactosyl-1,3-N-acetylglucosamine; Lacto-N-biose I, b-Methyl Glycoside; BETA-D-GAL-[1-]-D-GLCNAC; Lewis c; Glucopyranose Gal1-b-3-GlcNAc; GAL-BETA1-3GLCNAC; β-D-Gal-(1→3)-D-GlcNAc; O-beta-D-Galactopyranosyl-N-acetylglucosamine, Lacto-N-biose 1, Gal1-beta-3-GlcNAc

物化性质

• 密度: 1.64g/cm3
• 沸点: 795.5ºC at 760 mmHg
• 熔点: 165-167ºC
• 分子式: C₁₄H₂₅NO₁₁
• 分子量: 383.34800
• 闪点: 434.9ºC
• 精确质量: 383.14300
• PSA: 206.24000
• 折射率: 1.623

生物活性

• 描述: 乳糖-N-二糖I(Galβ1-3GlcNAc)作为内源性代谢产物,是幽门螺杆菌α1,2-岩藻糖基转移酶的受体[1]。
• 相关类别:
  研究领域 >> 内分泌
• 体外研究: 乳糖-N-二糖I是幽门螺杆菌α1,2-岩藻糖基转移酶的受体[1]。
• 参考文献:

  [1]. Valli M, et al. Beta-1,3-galactosyltransferase and alpha-1,2-fucosyltransferase involved in the biosynthesis of type-1-chain carbohydrate antigens in human colon adenocarcinoma cell lines. Eur J Biochem. 1998;256(2):494-501.

合成路线

63-42-3 ~% 50787-09-2

文献：Allessandrini et al. Journal of Biological Chemistry, 1956 , vol. 220, p. 71,75

133-89-1 ~% 50787-09-2

文献：Nishimoto, Mamoru; Kitaoka, Motomitsu Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 8 p. 2101 - 2104

2956-16-3 ~% 50787-09-2

文献：Nishimoto, Mamoru; Kitaoka, Motomitsu Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 8 p. 2101 - 2104

7512-17-6 59-56-3 ~% 50787-09-2

文献：Nishimoto, Mamoru; Kitaoka, Motomitsu Bioscience, Biotechnology and Biochemistry, 2007 , vol. 71, # 8 p. 2101 - 2104

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