519-65-3

• 常用中文名：AMDOPH 化学试剂
• 常用英文名：N'-acetyl-2-(dimethylamino)-N'-methyl-2-oxo-N-phenylacetohydrazide
• CAS号：519-65-3
• 分子式：C₁₃H₁₇N₃O₃
• 分子量：263.29200
• 发布时间：2016-03-03 08:48:37
• 更新时间：2025-08-26 11:26:16

名称

• 中文名: AMDOPH 化学试剂
• 英文名: dioxoaminopyrine
• 中文别名: 氨基比林杂质1; 双氧基氨基比林
• 英文别名: N,N-Dimethyl-2-oxo-2-(1-phenyl-2-acetyl-2-methylhydrazino)acetamide; 2-[[ethanoyl(methyl)amino]-phenyl-amino]-N,N-dimethyl-2-oxo-ethanamide; 1-Acetyl-1,5,5-triMethyl-2- phenylseMioxaMazide; α-(DiMethylaMidooxalyl)-β,β-Methylacetylphenylhydrazine; 1-acetyl-1-methyl-2-dimethyl-oxamoyl-2-phenylhydrazide; Dimethylaminooxoessigsaeure-2-acetyl-2-methyl-1-phenylhydrazid; DioxyaMinopyrine; 2-(N-[acetyl(methyl)amino]anilino)-N,N-dimethyl-2-oxoacetamide; N-Methyl-N'-phenyl-N'-(N,N-dimethyloxamoyl)acetohydrazide; DioxoaMinopyrine; Acetic acid, 2-(dimethylamino)-2-oxo-, 2-acetyl-2-methyl-1-phenylhydrazide; 1-acetyl-1-methyl-2-dimethyl-oxamoyl-2-phenyl-hydrazine; 1-Acetyl-1,5,5-triMethyl-2-phenylseMioxaMazide; 2-(N-[acetyl(methyl)amino]anilino)-2-keto-N,N-dimethyl-acetamide; N'-Acetyl-N'-methyl-2-(dimethylamino)-2-oxo-N-phenylacetohydrazide; Dioxypyramidon; Dioxyaminopyrine; 2-(DiMethylaMino)-2-oxo-acetic Acid 2-Acetyl-2-Methyl-1-phenylhydrazide; 1-(1-Phenyl-2-acetyl-2-methylhydrazino)-2-(dimethylamino)-1,2-ethanedione; Semioxamazide,1-acetyl-2-phenyl-1,5,5-trimethyl; N-Acetyl-N'-dimethylaminooxalyl-N-methyl-N'-phenyl-hydrazin; Dioxoaminopyrine; EINECS 208-274-5

物化性质

• 密度: 1.219g/cm3
• 沸点: 360.6ºC at 760mmHg
• 分子式: C₁₃H₁₇N₃O₃
• 分子量: 263.29200
• 闪点: 146.3ºC
• 精确质量: 263.12700
• PSA: 60.93000
• LogP: 0.50110
• 折射率: 1.574

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VT5350000 CHEMICAL NAME : Semioxamazide, 1-acetyl-2-phenyl-1,5,5-trimethyl- CAS REGISTRY NUMBER : 519-65-3 BEILSTEIN REFERENCE NO. : 1822610 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C13-H17-N3-O3 MOLECULAR WEIGHT : 263.33 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1631 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 213,501,1951 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1066 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 213,501,1951 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 698 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 213,501,1951

安全

• 海关编码: 2928000090

合成路线

58-15-1 ~91% 519-65-3

文献：Duchstein, Hans-Juergen; Ruch-Zaske, Gabriela; Holzmann, Gerhard; Wollenberg, Eva; Weber, Horst Archiv der Pharmazie (Weinheim, Germany), 1988 , vol. 321, p. 25 - 27

50680-54-1 38604-70-5 ~% 519-65-3

文献：Charonnat; Delaby Bulletin des Sciences Pharmacologiques, 1930 , vol. 37, p. 75,85

58-15-1 7722-84-1 ~% 519-65-3 38604-70-5

文献：Charonnat; Delaby Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1929 , vol. 189, p. 851

上下游产品

上游产品  4
58-15-1 50680-54-1 38604-70-5 7722-84-1
下游产品  4
144-62-7 622-36-6 64-19-7 124-40-3

海关

海关编码	2928000090
中文概述	2928000090 其他肼（联氨）及胲（羟胺）的有机衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%