107880-74-0

• 常用中文名：3-[[[2-[(氨基亚胺甲基)氨基]-4-噻唑基]甲基]硫基]丙酸
• 常用英文名：3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]propanoic acid
• CAS号：107880-74-0
• 分子式：C₈H₁₂N₄O₂S₂
• 分子量：260.33600
• 发布时间：2018-12-02 16:04:19
• 更新时间：2026-09-10 17:10:15

名称

• 中文名: 3-[[[2-[(氨基亚胺甲基)氨基]-4-噻唑基]甲基]硫基]丙酸
• 英文名: 3-[[2-(diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]propanoic acid
• 中文别名: 法莫替丁杂质F D; 法莫替丁酸杂质; 法莫替丁相关物质F 标准品; 3-((2-胍噻唑-4-基)甲基)硫代)丙酸 (法莫替丁杂质); 法莫替丁杂质F; 3-氯-N-氨磺酰丙酰盐酸盐(法莫替丁杂质); 法莫替丁酸杂质6; 法莫替丁酸(杂质F); 法莫替丁相关化合物F; 法莫替丁杂质F盐酸盐; 法莫替丁杂质F 标准品; 法莫替丁杂质6(法莫替丁杂质F); 法莫替丁 杂质 F(法莫替丁 相关化合物 F); 法莫替丁相关物质F
• 英文别名: 3-[[[2-[(Diaminomethylene)amino]thiazol-4-yl]methyl]sulphanyl]propanoic acid; Famotidine Related Compound-F / FamotidineImpurity-F; Imp. F :3-[[[2-[(Diaminomethylene)-amino]thiazol-4-yl]methyl]sulfanyl]-propanoic Acid; FAMOTIDINE IMPURITY F HYDROCHLORIDE; Famotidine propionic acid; UNII-3L58HV8ZAU; Propanoic acid, 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]; Famotidine Related Compound F; Famotidine Acid; 3-(((2-Guanidinothiazol-4-yl)methyl)thio)propanoic acid; Famotidine Impurity F (Famotidine Related Compound F); Famotidine Impurity F,Famotidine Related Compound C; Famotidine Imp. F : 3-[[[2-[(Diaminomethylene) aminothiazol-4-ylmethylsulphanylpropanoic Acid; Famotidine Impurity F; Famotidine Acid Impurity; 3-[[[2-[(Diaminomethylene)-amino]thiazol-4-yl]methyl]sulfanyl]-propanoic Acid; 3-(((2-Guanidinothiazol-4-yl)methyl)thio)propanoic acid (Famotidine Impurity); Imidacloprid Impurity 23; Famotidine Impurity F/ Famotidine Related Compound F (Famotidine Acid Impurity); 3-[[[2-[(DiaMinoMethylene)amino]thiazol-4-yl]Methyl]thio]propanoic acid; Famotidine Impurity 6(Famotidine Impurity F); Famotidine Related Compound F (3-[[2-(diaminomethyleneamino)thiazol-4-yl]methylthio]propanoic acid); FaMotidine Acid IMpurity; Famotidine Impurity 6; 3-[[[2-[(AMinoiMinoMethyl)amino]-4-thiazolyl]Methyl]thio]propanoic Acid; Famotidine Related Compound F (25 mg) (3-[[2-(diaminomethyleneamino)thiazol-4-yl]methylthio]propanoic acid)

物化性质

• 密度: 1.63±0.1 g/cm3
• 熔点: 256 ºC
• 分子式: C₈H₁₂N₄O₂S₂
• 分子量: 260.33600
• 精确质量: 260.04000
• PSA: 165.63000
• LogP: 2.02940
• 水溶解性: Slightly soluble (2 g/L)

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

76824-35-6 ~75% 107880-74-0

文献：Yanagisawa, Isao; Hirata, Yasufumi; Ishii, Yoshio Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1787 - 1793

76823-94-4 ~% 107880-74-0

文献：Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1787 - 1793

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