19888-56-3

• 常用中文名：氟扎可特
• 常用英文名：Fluazacort
• CAS号：19888-56-3
• 分子式：C₂₅H₃₀FNO₆
• 分子量：459.50700
• 发布时间：2018-07-25 19:58:36
• 更新时间：2026-10-27 16:03:48
• Fluazacort is an anti-inflammatory.

名称

• 中文名: 氟扎可特
• 英文名: fluazacort
• 英文别名: l-6400; 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 21-(acetyloxy)-9-fluoro-11-hydroxy-2'-methyl-, (11β,16β); Fluazacortum; 21-acetoxy-9-fluoro-11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 9α-Fluoro-11β,21-dihydroxy-3,20-dioxo-1,4-pregnadieno[17α,16α-d]-2-Methyloxazoline 21-Acetate; (5'β)-9-Fluoro-11β,21-dihydroxy-2'-methylpregnano[17,16-d]oxazole-1,4-diene-3,20-dione 21-acetate; (16β)-21-(Acetoxy)-9-fluoro-11β-hydroxy-2'-methylpregnano[17,16-d]oxazole-1,4-diene-3,20-dione; Azacortid; L-6400; (11β,16β)-21-(Acetyloxy)-9-fluoro-11-hydroxy-2'-Methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione

物化性质

• 密度: 1.43g/cm3
• 沸点: 592.4ºC at 760mmHg
• 分子式: C₂₅H₃₀FNO₆
• 分子量: 459.50700
• 闪点: 312.1ºC
• 精确质量: 459.20600
• PSA: 102.26000
• LogP: 2.09090
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.642

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TU4157052 CHEMICAL NAME : 5'-beta-H-Pregna-1,4-dieno(17,16-d)oxazole-3,20-dione , 9-fluoro-11-beta,21-dihydroxy- 2'-methyl-, 21-acetate CAS REGISTRY NUMBER : 19888-56-3 LAST UPDATED : 198503 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C25-H30-F-N-O6 MOLECULAR WEIGHT : 459.56 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 580 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 12,396,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 54 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : MDACAP Medicamentos de Actualidad. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1965- Volume(issue)/page/year: 12,396,1976

合成路线

19890-69-8 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

13649-87-1 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

19890-68-7 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

19890-70-1 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

19890-71-2 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

13649-86-0 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

16119-57-6 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

16119-56-5 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

108-24-7 14484-48-1 ~% 19888-56-3

文献：Steroids, , vol. 13, p. 383 - 397

上下游产品

上游产品  4
13649-87-1 16119-56-5 108-24-7 14484-48-1
下游产品  0