452105-33-8

• 常用中文名：5-[(5-氟-1,2-二氢-2-氧代-3H-吲哚-3-亚基)甲基]-2,4-二甲基-1H-吡咯-3-羧酸
• 常用英文名：5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid
• CAS号：452105-33-8
• 分子式：C₁₆H₁₃FN₂O₃
• 分子量：300.28400
• 发布时间：2016-04-23 15:39:37
• 更新时间：2026-07-01 18:04:57

名称

• 中文名: 5-[(5-氟-1,2-二氢-2-氧代-3H-吲哚-3-亚基)甲基]-2,4-二甲基-1H-吡咯-3-羧酸
• 英文名: 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-carboxylic acid
• 中文别名: 舒尼替尼羧酸杂质; 5-(5-氟-2-氧代-1,2-二氢-吲哚-3-亚基甲基)-2,4-二甲基-1H-吡咯-3-羧酸; 5-((5-氟-2-氧代吲哚啉-3-亚基)甲基)-2,4-二甲基-1H-吡咯-3-羧酸; 5-(5-氟-2-氧代-1,2,二氢-吲哚-3-亚甲基)-2,4-二甲基-1H-吡咯-3-羧酸; 5-(5-氟-2-氧代-1,2-二氢-吲哚-3-亚甲基)-2,4-二甲基-1H-吡咯-3-甲酸
• 英文别名: 5(5Fluoro2oxo1,2dihydroindol3ylidenemethyl)2,4dimethyl1Hpyrrole3cboxylic Acid,5 (5 Fluoro 2 oxo 1,2 dihydro indol 3 ylidenemethyl) 2,4 dimethyl 1H pyrrole 3 cboxylic Acid; Sunitinib Malate 1; 1H-Pyrrole-3-cboxylic acid, 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl; 5-[(Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4 -dimethyl-1H-pyrrole-3-cboxylic acid; 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-cboxylic Acid; 5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-cboxylic Acid, 10 mM in DMSO; Sunitinib Cbaxylic Acid; 5-[(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)Methyl]-2,4-diMethyl-1H-pyrrole-3-cboxylic Acid; Sunitinib Cboxylic Acid Impurity; 5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-cboxylic acid; Sunitinib Process Impurity 1

物化性质

• 分子式: C₁₆H₁₃FN₂O₃
• 分子量: 300.28400
• 精确质量: 300.09100
• PSA: 85.68000
• LogP: 3.04660

合成路线

253870-02-9 56341-41-4 ~98% 452105-33-8

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365

2199-51-1 ~% 452105-33-8

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365

443-69-6 ~% 452105-33-8

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365

2199-59-9 ~% 452105-33-8

文献：Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 52, # 9 p. 360 - 365

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