122454-52-8

• 常用中文名：(2S,3AS,7AS)-1-[2-[乙氧基羰基-(S)-胺基]-(S)-丙酰基八氢吲哚-2-羧酸苄酯]
• 常用英文名：(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic Acid Benzyl Ester
• CAS号：122454-52-8
• 分子式：C₂₆H₃₈N₂O₅
• 分子量：458.59000
• 发布时间：2018-12-21 17:03:00
• 更新时间：2025-08-27 10:36:05

名称

• 中文名: (2S,3AS,7AS)-1-[2-[乙氧基羰基-(S)-胺基]-(S)-丙酰基八氢吲哚-2-羧酸苄酯]
• 英文名: benzyl 1-[2-[(1-ethoxy-1-oxopentan-2-yl)amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylate
• 中文别名: (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(乙氧基羰基)丁基]氨基]-1-氧代丙基]八氢-1H-吲哚-2-羧酸苄酯
• 英文别名: 1-[2-[(1-ethoxy-1-oxopentan-2-yl)amino]-1-oxopropyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid (phenylmethyl) ester; (phenylmethyl) 1-[2-[(1-ethoxy-1-oxidanylidene-pentan-2-yl)amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylate; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid benzyl ester; benzyl (2S,3aS,7aS)-1-{(2S)-2-[(1S)-1-(ethoxycarbonyl)-butylamino]-propionyl}-octahydro-1H-indole-2-carboxylate; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]propanoyl]octahydro-1H-indole-2-carboxylic acid benzyl ester; (2S,3aS,7aS)-1-{(S)-2-[(S)-1-ethoxycarbonyl-butylamino]-propionyl}-octahydro-indole-2-carboxylic acid benzyl ester; Perindopril benzyl salicylate; (2S,3aS,7aS)-1-{2-[1-(ethoxycarbonyl)-(S)-butylamine]-(S)-propionyl}octahydroindole-2-carboxylic acid benzyl ester; perindopril benzyl ester

物化性质

• 密度: 1.128g/cm3
• 沸点: 582.399ºC at 760 mmHg
• 分子式: C₂₆H₃₈N₂O₅
• 分子量: 458.59000
• 闪点: 306.024ºC
• 精确质量: 458.27800
• PSA: 84.94000
• LogP: 3.92820
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.53

合成路线

631914-56-2 50461-74-0 ~82% 122454-52-8

文献：US2007/88168 A1, ; Page/Page column 2 ;

83508-14-9 82834-12-6 ~89% 122454-52-8

文献：WO2007/17087 A1, ; Page/Page column 13 ;

94062-52-9 82834-12-6 ~99% 122454-52-8

文献：EP1679072 A1, ; Page/Page column 7 ;

83508-14-9 827622-31-1 ~78% 122454-52-8

文献：WO2005/37788 A1, ; Page/Page column 51 ;

94062-52-9 82834-12-6 121-44-8 ~94% 64407-57-4 详细

文献：WO2005/37788 A1, ; Page/Page column 42-43 ;

83508-14-9 748154-69-0 ~% 122454-52-8

文献：WO2005/37788 A1, ; Page/Page column 47 ;

83508-14-9 827622-31-1 ~% 149-30-4 122454-52-8

文献：Synthetic Communications, , vol. 35, # 2 p. 243 - 248

82834-12-6 ~% 122454-52-8

文献：Synthetic Communications, , vol. 35, # 2 p. 243 - 248

上下游产品

上游产品  7
50461-74-0 83508-14-9 82834-12-6 94062-52-9
827622-31-1 121-44-8 748154-69-0
下游产品  1
82834-16-0