193001-59-1

• 常用中文名：4-(4-氯-2-氟苯基氨基)-7-羟基-6-甲氧基喹唑啉
• 常用英文名：4-(4-chloro-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one
• CAS号：193001-59-1
• 分子式：C₁₅H₁₁ClFN₃O₂
• 分子量：319.71800
• 发布时间：2018-10-21 10:29:07
• 更新时间：2024-01-08 15:38:55

名称

• 中文名: 4-(4-氯-2-氟苯基氨基)-7-羟基-6-甲氧基喹唑啉
• 英文名: 4-(4-chloro-2-fluoroanilino)-6-methoxy-1H-quinazolin-7-one
• 英文别名: 7-Quinazolinol,4-[(4-chloro-2-fluorophenyl)amino]-6-methoxy; 7-hydroxy-6-methoxy-4-(2-fluoro-4-chlorophenylamino)quinazoline; 4-[(4-chloro-2-fluorophenyl)amino]-6-methoxyquinazolin-7-ol; 4-(4-chloro-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline; 4-(4-chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazoline; N-(4-chloro-2-fluorophenyl)-7-hydroxy-6-methoxy-4-quinazolinylamine

物化性质

• 分子式: C₁₅H₁₁ClFN₃O₂
• 分子量: 319.71800
• 精确质量: 319.05200
• PSA: 67.01000
• LogP: 3.54080

合成路线

57946-56-2 ~% 193001-59-1

文献：Gao, Mingzhang; Lola, Christian M.; Wang, Min; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3222 - 3226

60547-98-0 ~% 193001-59-1

文献：Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389

179688-01-8 ~% 193001-59-1

文献：Hennequin, Laurent F.; Thomas, Andrew P.; Johnstone, Craig; Stokes, Elaine S. E.; Ple, Patrick A.; Lohmann, Jean-Jacques M.; Ogilvie, Donald J.; Dukes, Mike; Wedge, Steve R.; Curwen, Jon O.; Kendrew, Jane; Lambert-Van Der Brempt, Christine Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5369 - 5389

162364-72-9 ~% 193001-59-1

文献：Gao, Mingzhang; Lola, Christian M.; Wang, Min; Miller, Kathy D.; Sledge, George W.; Zheng, Qi-Huang Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 11 p. 3222 - 3226