81994-68-5

• 常用中文名：4-Butylamino-N-(2-(diethylamino)ethyl)phthalimide hydrochloride
• 常用英文名：4-Butylamino-N-(2-(diethylamino)ethyl)phthalimide hydrochloride
• CAS号：81994-68-5
• 分子式：C₁₈H₂₈ClN₃O₂
• 分子量：353.88700
• 发布时间：2017-07-15 09:31:13
• 更新时间：2025-08-27 09:37:23

名称

• 英文名: 5-(butylamino)-2-[2-(diethylamino)ethyl]isoindole-1,3-dione,hydrochloride

物化性质

• 沸点: 464.6ºC at 760 mmHg
• 分子式: C₁₈H₂₈ClN₃O₂
• 分子量: 353.88700
• 闪点: 234.8ºC
• 精确质量: 353.18700
• PSA: 52.65000
• LogP: 3.64930
• 储存条件: 库房通风低温干燥,与食品原料类分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TI4204000 CHEMICAL NAME : Phthalimide, 4-butylamino-N-(2-(diethylamino)ethyl)-, hydrochloride CAS REGISTRY NUMBER : 81994-68-5 LAST UPDATED : 198609 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C18-H27-N3-O2.Cl-H MOLECULAR WEIGHT : 353.94 WISWESSER LINE NOTATION : T56 BVNVJ C2N2&2 GM4 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 580 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 66 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 130 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 312 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 71 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 67 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3700 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 16,59,1981

合成路线

77763-90-7 ~% 81994-68-5

文献：Da Settimo; Primofiore; Ferrarini; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 1 p. 59 - 64

5434-21-9 ~% 81994-68-5

文献：Da Settimo; Primofiore; Ferrarini; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 1 p. 59 - 64

77763-89-4 ~% 81994-68-5

文献：Da Settimo; Primofiore; Ferrarini; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 1 p. 59 - 64

100-36-7 ~% 81994-68-5

文献：Da Settimo; Primofiore; Ferrarini; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 1 p. 59 - 64