CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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UA8470000
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CHEMICAL NAME :
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2-Propanol, 1-(tert-butylamino)-3-(3-methyl-2-nitrophenoxy)-, DL-
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CAS REGISTRY NUMBER :
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86166-58-7
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LAST UPDATED :
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199707
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DATA ITEMS CITED :
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15
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MOLECULAR FORMULA :
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C14-H22-N2-O4
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MOLECULAR WEIGHT :
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282.38
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WISWESSER LINE NOTATION :
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WNR B1 FO1YQ1MX1&1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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76243 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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9 gm/kg/26W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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18 gm/kg/26W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Liver - tumors
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TYPE OF TEST :
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Morphological transformation
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TYPE OF TEST :
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DNA damage
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TYPE OF TEST :
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Unscheduled DNA synthesis
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TYPE OF TEST :
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DNA damage
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TYPE OF TEST :
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DNA inhibition
MUTATION DATA
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TEST SYSTEM :
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Rodent - rat
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DOSE/DURATION :
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100 mg/kg
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REFERENCE :
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TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 13,18,1985 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,395,1986
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