27475-14-5

• 常用中文名：5-(2-溴乙酰基)-2-苄氧基苯甲酸甲酯
• 常用英文名：5-bromoacetyl-2-bensyloxybenzoic acid methyl ester
• CAS号：27475-14-5
• 分子式：C₁₇H₁₅BrO₄
• 分子量：363.20300
• 发布时间：2018-08-01 20:42:50
• 更新时间：2026-07-15 12:40:35

名称

• 中文名: 5-(2-溴乙酰基)-2-苄氧基苯甲酸甲酯
• 英文名: 5-bromoacetyl-2-bensyloxybenzoic acid methyl ester
• 中文别名: 沙美特罗杂质16沙丁胺醇杂质42; 沙丁胺醇杂质80; 2-(苄氧基)-5-(2-溴乙酰基)苯甲酸甲酯; 沙丁胺醇杂质74; 沙美特罗杂质16; 沙美特罗杂质16对照品; 沙丁胺醇杂质IIA-3
• 英文别名: 2-benzyloxy-5-(2-bromoacetyl)benzoic acid methyl ester; Benzoic acid, 5-(2-bromoacetyl)-2-(phenylmethoxy)-, methyl ester; Salmeterol Impurity 16 Salbutamol Impurity 42; Benzyl Albuterol Impurity; Salbutamol Impurity IIa-3; estere metilico dell'acido 5-bromoacetil-2-benzilossibenzoico; Salbutamol Impurity 80; Methyl 2-(benzyloxy)-5-(2-broMoacetyl)benzoate; Salmeterol Impurity 37; Salbutamol Impurity 74; methyl 2-benzyloxy-5-bromoacetylbenzoate; 2-benzyloxy-5-bromoacetylbenzoic acid,methyl ester; Methyl-5-(2-broMoacetyl)-2-benzyloxy benzoate; Salmeterol Impurity 16; 5-BROMOACETYL-2-BENSYLOXYBENZOIC ACID METHYL ESTER; 2-benzyloxy-5-bromoacetylbenzoic acid; 5-Bromoacetyl-2-bensyloxbenzoic acid methyl ester

物化性质

• 密度: 1.414g/cm3
• 沸点: 501.7ºC at 760 mmHg
• 分子式: C₁₇H₁₅BrO₄
• 分子量: 363.20300
• 闪点: 257.2ºC
• 精确质量: 362.01500
• PSA: 52.60000
• LogP: 3.62980
• 蒸汽压: 3.38E-10mmHg at 25°C
• 折射率: 1.592

安全

• 海关编码: 2918990090

合成路线

27475-09-8 ~81% 27475-14-5

文献：CADILA HEALTHCARE LIMITED; DWIVEDI, Shriprakash, Dhar; SHAH, Niraj, Shyamlal Patent: WO2012/32546 A2, 2012 ; Location in patent: Page/Page column 25-26 ;

16475-90-4 ~% 27475-14-5

文献：Meglio, P. de; Carissimi, M.; Ravenna, F.; Gentili, P.; Manzardo, S. Farmaco, Edizione Scientifica, 1980 , vol. 35, # 3 p. 202 - 230

100-44-7 ~% 27475-14-5

文献：CADILA HEALTHCARE LIMITED; DWIVEDI, Shriprakash, Dhar; SHAH, Niraj, Shyamlal Patent: WO2012/32546 A2, 2012 ;

27475-09-8 7789-45-9 ~% 27475-14-5

文献：Asahi Kasei Kogyo Kabushiki Kaisha Patent: US6037362 A1, 2000 ;

100-39-0 ~% 27475-14-5

文献：Jacobsen, John R.; Choi, Seok Ki; Combs, Jesse; Fournier, Eric J.L.; Klein, Uwe; Pfeiffer, Juergen W.; Thomas, G. Roger; Yu, Cecile; Moran, Edmund J. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 1213 - 1218

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%