1196052-98-8

• 常用中文名：N-[(1S)-3-[3-(反-2-氨基环丙基)苯氧基]-1-(苄基氨基甲酰)丙基]苯甲酰胺盐酸盐
• 常用英文名：N-((2S)-4-(3-(2-aminocyclopropyl)phenoxy)-1-(benzylamino)-1-oxobutan-2-yl)benzamidehydrochloride
• CAS号：1196052-98-8
• 分子式：C₂₇H₃₀ClN₃O₃
• 分子量：479.99800
• 发布时间：2018-10-13 11:49:25
• 更新时间：2024-04-03 14:41:05

名称

• 中文名: N-[(1S)-3-[3-(反-2-氨基环丙基)苯氧基]-1-(苄基氨基甲酰)丙基]苯甲酰胺盐酸盐
• 英文名: (S)-trans-N-3-{3-(2-aminocyclopropyl)phenoxy}-1-benzylcarbamoyl propylbenzamide hydrochloride
• 英文别名: N-((2S)-4-(3-(2-aminocyclopropyl)phenoxy)-1-(benzylamino)-1-oxobutan-2-yl)benzamide hydrochloride; N-[(1S)-3-[3-(TRANS-2-AMINOCYCLOPROPYL)PHENOXY]-1-(BENZYLCARBAMOYL)PROPYL]BENZAMIDE HYDROCHLORIDE; N-((2S)-4-(3-(2-aminocyclopropyl)phenoxy)-1-(benzylamino)-1-oxobutan-2-yl)benzamidehydrochloride

物化性质

• 分子式: C₂₇H₃₀ClN₃O₃
• 分子量: 479.99800
• 精确质量: 479.19800
• PSA: 93.45000
• LogP: 5.66920
• 储存条件: 2-8°C，密封，干燥

MSDS

Section I.Chemical Product and Company Identification Chemical NameN-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy] -1-(benzylcarbamoyl)propyl]benzamide Hydrochloride Portland OR Benzamide, Synonym N-[(1S)-3-[3-(2-aminocyclopropyl)phenoxy]-1- [[(phenylmethyl)amino]carbonyl]propyl]-, hydrochloride (1:1) (CA INDEX NAME) Chemical FormulaC27H29N3O3·HCl 1196052-98-8 CAS Number Section II.Composition and Information on Ingredients Chemical NameCAS Number Percent (%)TLV/PELToxicology Data N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy]1196052-98-8Min. 97.0 Not available.Not available. -1-(benzylcarbamoyl)propyl]benzamide Hydrochloride(HPLC) Section III. Hazards Identification No specific information is available in our data base regarding the toxic effects of this material for humans. However, Acute Health Effects exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. CARCINOGENIC EFFECTS : Not available. Chronic Health Effects MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.First Aid Measures Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 Eye Contact minutes. Get medical attention. Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. InhalationIf the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not improve. IngestionINDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic material was ingested; the absence of such signs, however, is not conclusive. Section V.Fire and Explosion Data Not available. Auto-Ignition FlammabilityMay be combustible at high temperature. Flammable LimitsNot available. Flash PointsNot available. Combustion ProductsThese products are toxic carbon oxides (CO, CO2), nitrogen oxides (NO, NO2), halogenated compounds. WARNING: Highly toxic HCl gas is produced during combustion. Fire HazardsNot available. Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards Risks of explosion of the product in presence of static discharge: Not available. Continued on Next Page N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy] -1-(benzylcarbamoyl)propyl]benzamide Hydrochloride Fire Fighting Media SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. DO NOT use water jet. and Instructions Consult with local fire authorities before attempting large scale fire-fighting operations. Section VI.Accidental Release Measures Spill CleanupHygroscopic material. Heat sensitive material. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any Instructions contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on disposal. Section VII. Handling and Storage Handling and StorageHYGROSCOPIC. HEAT SENSITIVE. STORE UNDER ARGON. REFRIGERATE. Keep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool place. Avoid excessive heat and light. Information Do not breathe dust. Always store away from incompatible compounds such as oxidizing agents, moisture. Section VIII. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSplash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent. Exposure LimitsNot available. Section IX. Physical and Chemical Properties Solid. (Crystal, powder. White, yellowishSolubility Physical state @ 20°CNot available. grey.) Not available. Specific Gravity Molecular Weight480.00Partition Coefficient Not available. Boiling PointNot available.Vapor PressureNot applicable. 139°C (282.2°F)Not available. Melting PointVapor Density Refractive IndexNot available.VolatilityNot available. Not available.Not available. Critical TemperatureOdor ViscosityNot available.TasteNot available. Section X.Stability and Reactivity Data This material is stable if stored under proper conditions. (See Section VII for instructions) Stability Conditions of InstabilityAvoid excessive heat and light. Hygroscopic; keep container tightly closed. Incompatibilities Reactive with oxidizing agents, moisture. Section XI. Toxicological Information Not available. RTECS Number Eye Contact. Ingestion. Inhalation. Routes of Exposure Not available. Toxicity Data Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available. MUTAGENIC EFFECTS : Not available. TERATOGENIC EFFECTS : Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Acute Toxic EffectsNo specific information is available in our data base regarding the toxic effects of this material for humans. However, exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this compound. Continued on Next Page N-[(1S)-3-[3-(trans-2-Aminocyclopropyl)phenoxy] -1-(benzylcarbamoyl)propyl]benzamide Hydrochloride Section XII.Ecological Information Not available. Ecotoxicity Environmental FateNot available. Section XIII. Disposal Considerations Recycle to process, if possible. Consult your local regional authorities. You may be able to dissolve or mix material with a Waste Disposal combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section XIV. Transport Information DOT ClassificationNot a DOT controlled material (United States). PIN NumberNot applicable. Proper Shipping NameNot applicable. Packing Group (PG)Not applicable. DOT Pictograms Section XV. Other Regulatory Information and Pictograms TSCA Chemical InventoryThis product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40 CFR 720.36 (C) for those products not on the inventory list: (EPA) (i) These products are supplied solely for use in research and development by or under the supervision of a technically qualified individual as defined in 40 CFR 720.0 et sec. (ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be supplied on an MSDS sheet. WHMIS ClassificationNot controlled under WHMIS (Canada). (Canada) EINECS Number (EEC)Not available. EEC Risk Statements Not available. SECTION 16 - ADDITIONAL INFORMATION N/A