222030-63-9

• 常用中文名：康布瑞汀磷酸二钠
• 常用英文名：fosbretabulin disodium
• CAS号：222030-63-9
• 分子式：C₁₈H₂₁O₈P
• 分子量：396.32800
• 发布时间：2018-04-20 08:00:00
• 更新时间：2026-07-15 17:04:24

名称

• 中文名: 康布瑞汀磷酸二钠
• 英文名: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl] dihydrogen phosphate
• 中文别名: 康普瑞汀磷酸; 康普瑞汀 (游离态); 康普瑞汀磷酸酯; 康普立停 A4磷酸酯
• 英文别名: [2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenoxy]phosphonic acid; 2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate; disodium 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl phosphate; Combretastatin A-4 phosphate; Fosbretabulin disodium salt; CA 4DP; (Z)-2-Methoxy-5-(3,4,5-trimethoxystyryl)phenyl dihydrogen phosphate; combretastatin A-4 dihydrogen phosphate; Phenol, 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate, sodium salt (1:2); Combretastatin A4 disodium phosphate; Fosbretabulin [free base]; Fosbretabulin sodium; combretastatin A-4 phosphate, Fosbretabulin; CoMbretastatin A4 disodiuM phosphate(CA4P); Disodium 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenyl phosphate; combretastatin A-4 phosphoric acid; Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate); UNII-I5590ES2QZ; Fosbretabulin

物化性质

• 密度: 1.342g/cm3
• 沸点: 611.8ºC at 760mmHg
• 分子式: C₁₈H₂₁O₈P
• 分子量: 396.32800
• 闪点: 323.8ºC
• 精确质量: 396.09700
• PSA: 113.49000
• LogP: 3.36290
• 蒸汽压: 7.99E-16mmHg at 25°C
• 折射率: 1.609

合成路线

117048-62-1 ~94% 222030-63-9

文献：OXIGENE, INC. Patent: WO2008/103415 A2, 2008 ; Location in patent: Page/Page column 15 ;

145545-15-9 ~% 222030-63-9

文献：US7018987 B1, ; Page/Page column 12 ;

208465-89-8 ~% 222030-63-9

文献：US7018987 B1, ; Page/Page column 12 ;

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