79944-58-4

• 常用中文名：亚达唑散
• 常用英文名：idazoxan
• CAS号：79944-58-4
• 分子式：C₁₁H₁₂N₂O₂
• 分子量：204.22500
• 发布时间：2018-10-03 14:03:32
• 更新时间：2026-07-21 15:09:08

名称

• 中文名: 亚达唑散
• 英文名: idazoxan
• 中文别名: 2-(1,4-苯并二噁烷-2-基)-4,5-二氢-1H-咪唑; 2-(1,4-苯并二烷-2-基)-4,5-二氢-1H-咪唑; 咪唑克生
• 英文别名: dl-Idazoxan; Idazoxane; 1,4-Benzodioxin, 1H-iMidazole deriv; IDAZOXAN; Idazoxane [French]; RaceMic idazoxan; Idazoxanum; 2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; Idezoxane; 2-(1-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin; 2-(2,3-dihydro-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole; RX-781094; 2-(2-Imidazoline-2-yl)-2,3-dihydro-1,4-benzodioxin; Idazoxanum [Latin]; [125I]-Idazoxan; Idazoxano [Spanish]; 1H-IMidazole, 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro; 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole; Idazoxano; 2-(1,4-benzodioxan-2-yl)-2-imidazoline; [3H]-Idazoxan

物化性质

• 密度: 1.39 g/cm3
• 沸点: 397ºC at 760 mmHg
• 分子式: C₁₁H₁₂N₂O₂
• 分子量: 204.22500
• 精确质量: 204.09000
• PSA: 42.85000
• LogP: 0.59250
• 折射率: 1.665

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NI4804509 CHEMICAL NAME : 1H-Imidazole, 4,5-dihydro-2-(2,3-dihydro-1,4-benzodioxin-2-yl)- CAS REGISTRY NUMBER : 79944-58-4 LAST UPDATED : 199709 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C11-H12-N2-O2 MOLECULAR WEIGHT : 204.25 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 85 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 25,557,1990

合成路线

1008-92-0 ~% 79944-58-4

文献：Journal of Medicinal Chemistry, , vol. 26, # 6 p. 823 - 831

79944-55-1 107-15-3 ~% 79944-58-4

文献：Journal of Medicinal Chemistry, , vol. 26, # 6 p. 823 - 831

84687-14-9 ~% 79944-58-4

文献：US2005/90537 A1, ; Page/Page column 11 ;

92405-52-2 ~% 79944-58-4 89197-25-1 92405-50-0 详细

文献：Journal of Heterocyclic Chemistry, , vol. 21, # 1 p. 77 - 80

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