35285-68-8

• 常用中文名：尼泊金乙酯钠盐
• 常用英文名：Sodium ethyl p-hydroxybenzoate
• CAS号：35285-68-8
• 分子式：C₉H₉NaO₃
• 分子量：188.156
• 相关类别： 有机原料 有机金属盐
• 发布时间：2018-09-14 12:05:02
• 更新时间：2024-01-03 16:00:54
• 【用途一】
  本品为水溶性防腐剂,主要特点是安全、高效、广谱抗菌。广泛应用于医药工业 （中草药、中成药剂的配制；医疗器械消毒）；食品工业（乳制品、腌制品、饮料、果 汁、果冻、糕点等）；纺织工业（纺织品、棉纱、化纤）的防腐。以及其他如化妆品、 饲料、日用工业品的防腐。20公斤纸板桶,内复合铝膜袋。

名称

• 中文名: 尼泊金乙酯钠盐
• 英文名: sodium,4-ethoxycarbonylphenolate
• 中文别名: 羟苯乙酯钠; 尼泊金乙酯钠; 4-羟基苯甲酸乙酯钠盐; 对羟基苯甲酸乙酯钠
• 英文别名: MFCD00016475; 4-Hydroxy-benzoesaeure-aethylester,Natrium-Salz; EINECS 252-487-6; UNII-Z0D00IVA10; 4-Hydroxybenzoic acid,ethyl ester,sodium salt; Ethylparaben,sodium salt; sodium salt of ethyl-4-hydroxybenzoate; Benzoic acid, 4-hydroxy-, ethyl ester, sodium salt (1:1); sodium 4-carboethoxyphenolate; sodium salt of p-hydroxy ethylbenzoate; E215; Sodium 4-ethoxycarbonylphenoxide; Sodium 4-(ethoxycarbonyl)phenolate; ethyl 4-hydroxybenzoate sodium salt; Ethyl p-hydroxybenzoate,sodium salt; Sodium ethylparaben; p-hydroxybenzoic acid ethyl ester sodium salt; Sodium ethyl p-hydroxybenzoate

物化性质

• 沸点: 297.5ºC at 760 mmHg
• 分子式: C₉H₉NaO₃
• 分子量: 188.156
• 闪点: 120.3ºC
• 精确质量: 188.044937
• PSA: 49.36000
• LogP: 2.00710
• 外观性状: 固体
• 储存条件: 室温，干燥

MSDS

Section 1. Chemical Product and Company Identification Ethylparaben Sodium Common Name/ Trade Name Ethylparaben Sodium Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs. Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Not available. Flash Points Flammable LimitsNot available. Products of CombustionThese products are carbon oxides (CO, CO2). Fire Hazards in Presence of Slightly flammable to flammable in presence of heat. Various Substances Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards in Risks of explosion of the product in presence of static discharge: Not available. Presence of Various Substances SMALL FIRE: Use DRY chemical powder. Fire Fighting Media LARGE FIRE: Use water spray, fog or foam. Do not use water jet. and Instructions Special Remarks onAs with most organic solids, fire is possible at elevated temperatures Fire Hazards Special Remarks on Explosion Not available. Hazards Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7. Handling and Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do Precautions not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, reducing agents. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Ethylparaben Sodium Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Crystals solid.)OdorNot available. TasteNot available. Molecular Weight188.17 g/mole Off-white. Color Not available. pH (1% soln/water) Boiling PointNot available. Not available. Melting Point Critical TemperatureNot available. Not available. Specific Gravity Vapor PressureNot applicable. Vapor DensityNot available. Not available. Volatility Odor ThresholdNot available. Not available. Water/Oil Dist. Coeff. Ionicity (in Water)Not available. Dispersion PropertiesNot available. SolubilityNot available. Section 10. Stability and Reactivity Data StabilityThe product is stable. Not available. Instability Temperature Conditions of InstabilityExcess heat, incompatible materials Incompatibility with various Reactive with oxidizing agents, reducing agents. substances CorrosivityNot available. Special Remarks onNot available. Reactivity Special Remarks onNot available. Corrosivity PolymerizationWill not occur. Ethylparaben Sodium Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. Toxicity to AnimalsAcute oral toxicity (LD50): 2500 mg/kg [Mouse]. Chronic Effects on Humans Not available. Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Humans Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherAcute Potential Health Effects: Toxic Effects on HumansSkin: May cause skin irritation. Eyes: May cause eye irritation. Inhalation: Dust may cause respiratory tract irritation. Ingestion: Expected to be a low hazard. May affect behavior/central nervous system/nervous system (ataxia, somnolence, flaccid paralysis) Section 12. Ecological Information Not available. Ecotoxicity BOD5 and CODNot available. Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the ProductsThe product itself and its products of degradation are not toxic. of Biodegradation Special Remarks on theNot available. Products of Biodegradation Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14. Transport Information DOT ClassificationNot a DOT controlled material (United States). IdentificationNot applicable. Special Provisions forNot applicable. Transport DOT (Pictograms) Ethylparaben Sodium Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has Proposition 65found to cause cancer which would require a warning under the statute: No products were found. Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No. 252-487-6). Canada: Listed on Canadian Domestic Substance List (DSL). China: Listed on National Inventory. Japan: Listed on National Inventory (ENCS). Korea: Not listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. Other ClassificationsWHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC)This product is not classifiedNot applicable. according to the EU regulations. Health Hazard HMIS (U.S.A.)1 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 1 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Ethylparaben Sodium SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DH2200000 CHEMICAL NAME : Benzoic acid, p-hydroxy-, ethyl ester, sodium deriv. CAS REGISTRY NUMBER : 35285-68-8 LAST UPDATED : 199107 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H9-O3.Na MOLECULAR WEIGHT : 188.17 WISWESSER LINE NOTATION : OR DVO2 &-NA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 520 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - ataxia REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956

安全

• 海关编码: 2909500000

合成路线

120-47-8 ~% 35285-68-8

文献：US4276431 A1, ;

1268380-09-1 ~99% 81256-74-8 35285-68-8

文献：Kim, Song-I; Hwang, So-Jeong; Jung, Eun-Mi; Um, Ik-Hwan Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 7 p. 2015 - 2018

上下游产品

上游产品  1
120-47-8
下游产品  0

海关

海关编码	2909500000
中文概述	2909500000. 醚酚、醚醇酚及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%