42267-27-6

• 常用中文名：N-(4-(2,5-二氧代-4-恶唑烷基)丁基)-2,2,2-三氟乙酰胺
• 常用英文名：N-(4-(2,5-Dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoroacetamide
• CAS号：42267-27-6
• 分子式：C₉H₁₁F₃N₂O₄
• 分子量：268.190
• 发布时间：2018-12-31 04:03:16
• 更新时间：2026-07-04 21:02:20

名称

• 中文名: N-(4-(2,5-二氧代-4-恶唑烷基)丁基)-2,2,2-三氟乙酰胺
• 英文名: N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide
• 中文别名: N-(4-(2,5-二氧代-4-噁唑烷基)丁基)-2,2,2-三氟乙酰胺; N-(4-(2,5-二氧代-4-恶唑烷基)丁基)-2,2,2-三氟乙酰胺LYS(TFA)-NCA; 格拉替雷单体; (S)-N-[4-(2,5-二氧代噁唑烷-4-基)丁基]-2,2,2-三氟乙酰胺; NΕ-三氟乙酰基-L-赖氨酸环内酸酐; 肌酸酐杂质4; LYS(TFA)-N-羧基环内酸酐; N6-三氟乙酰基-L-赖氨酸N-羧酸酐; NE-三氟乙酰基-L-赖氨酸环内酸酐; Nε-三氟乙酰基-L-赖氨酸环内酸酐; (S)-N-[4-(2,5-二氧代恶唑烷-4-基)丁基]-2,2,2-三氟乙酰胺; (S)-N-(4-(2,5-二氧噁唑烷-4-基)丁基)-2,2,2-三氟乙酰胺
• 英文别名: N6-Trifluoroacetyl-L-lysine N-Cboxyanhydride; L-Lys(TFA)-NCA; (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetaMide; N6-(Trifluoroacetyl)-N2-cboxy-L-Lysine anhydride; N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetaMide; L-Lysine-N-Trifluoroacetyl-N-Cboxyanhydride; N-Trifluoroacetyl L-Lysine N-Carboxy anhydride; trifluoroacetyl-L-lysine N-carboxyanhydride; e-Trifluoroacetyl-Lysine, NCA; (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)-butyl)-2,2,2-trifluoroacetamide; Acetamide,N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoro-,(S); N-Trifluoroacetyl-L-lysine N-cboxyanhydride; N-(4-(2,5-Dioxooxazolidin-4-yl); N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide; Creatinine Impurity 4; N-{4-[(4S)-2,5-Dioxo-1,3-oxazolidin-4-yl]butyl}-2,2,2-trifluoroacetamide; L-LYS(TFA)-NCA(42-6); N-[4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE; L-Lys(tfa)-NCA; Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifl; Lys(Tfa)-NCA; AcetaMide,N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro; Ne-trifluoroacetyl L-lysine intracyclic anhydride; Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluo; N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride; N-trifluoroacetyl lysine N-cboxyanhydride; N-[3-[(4S)-2,5-dioxooxazolidin-4-yl]propyl]-2,2,2-trifluoro-acetaMide; 4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE; Meloxicam Impurity 25; Lysine-TFA-NCA; Lys-NCA; (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide; Nsilon-Trifluoroacetyl-Nalpha-cboxy-L-lysine Anhydride

物化性质

• 密度: 1.4±0.1 g/cm3
• 熔点: 92-93ºC (DEC.)
• 分子式: C₉H₁₁F₃N₂O₄
• 分子量: 268.190
• 精确质量: 268.067078
• PSA: 84.50000
• LogP: 0.07
• 折射率: 1.437
• 储存条件: -20°C

安全

• 海关编码: 2934999090

合成路线

112139-31-8 ~87% 42267-27-6

文献：Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844

75-44-5 10009-20-8 ~68% 42267-27-6

文献：Cherevin; Gulevich; Popova; Zubreichuk; Knizhnikov Russian Journal of Organic Chemistry, 2007 , vol. 43, # 10 p. 1427 - 1431

10009-20-8 503-38-8 ~61% 42267-27-6

文献：Huesmann, David; Birke, Alexander; Klinker, Kristina; Tuerk, Stephan; Raeder, Hans Joachim; Barz, Matthias Macromolecules, 2014 , vol. 47, # 3 p. 928 - 936

32315-10-9 10009-20-8 ~% 42267-27-6

文献：Obeid, Rodolphe; Armstrong, Tracy; Peng, Xiaoju; Busse, Karsten; Kressler, Joerg; Scholz, Carmen Journal of Polymer Science, Part A: Polymer Chemistry, 2014 , vol. 52, # 2 p. 248 - 257

75-44-5 10009-20-8 ~% 42267-27-6 112139-30-7

文献：Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844

10009-20-8 ~% 42267-27-6

文献：Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844

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海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%