3780-72-1

• 常用中文名：Morsuximide
• 常用英文名：Morsuximide
• CAS号：3780-72-1
• 分子式：C₁₆H₂₀N₂O₃
• 分子量：288.34200
• 发布时间：2017-11-12 11:39:29
• 更新时间：2024-02-03 09:42:00

名称

• 英文名: 3-methyl-1-(morpholin-4-ylmethyl)-3-phenylpyrrolidine-2,5-dione
• 英文别名: Morsuximidum [INN-Latin]; 3-methyl-1-morpholin-4-ylmethyl-3-phenyl-pyrrolidine-2,5-dione; Morpholep; Succinimide,2-methyl-N-(morpholinomethyl)-2-phenyl; S 210; Morsuximida [INN-Spanish]; 2-Phenyl-2-methyl-N-morpholinomethyl-succinimid; Morfolep; Perlepsin; 1-Morpholinomethyl-3-methyl-3-phenylpyrrolidin-2,5-dion; Morsuximide; 2-Methyl-N-(morpholinomethyl)-2-phenylsuccinimide

物化性质

• 密度: 1.213g/cm3
• 沸点: 473ºC at 760mmHg
• 分子式: C₁₆H₂₀N₂O₃
• 分子量: 288.34200
• 闪点: 239.9ºC
• 精确质量: 288.14700
• PSA: 49.85000
• LogP: 0.86870
• 折射率: 1.567

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : WN3150000 CHEMICAL NAME : Succinimide, 2-methyl-N-(morpholinomethyl)-2-phenyl- CAS REGISTRY NUMBER : 3780-72-1 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C16-H20-N2-O3 MOLECULAR WEIGHT : 288.38 WISWESSER LINE NOTATION : T6N DOTJ A1- BT5VNVTJ D1 DR HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,266,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 480 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - analgesia REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 44,22,1981

安全

• 海关编码: 2934999090

合成路线

110-91-8 50-00-0 1497-17-2 ~82% 3780-72-1

文献：Obniska, Jolanta; Chlebek, Iwona; Kaminski, Krzysztof Archiv der Pharmazie, 2012 , vol. 345, # 9 p. 713 - 722

14231-67-5 ~% 3780-72-1

文献：Obniska, Jolanta; Chlebek, Iwona; Kaminski, Krzysztof Archiv der Pharmazie, 2012 , vol. 345, # 9 p. 713 - 722

上下游产品

上游产品  4
110-91-8 50-00-0 1497-17-2 14231-67-5
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%