1251570-77-0

• 常用中文名：(S)-3-(3-甲基丁酰基)吡咯烷-1-羧酸叔丁酯
• 常用英文名：(S)-1-BOC-3-(3-METHYLBUTANOYL)PYRROLIDINE
• CAS号：1251570-77-0
• 分子式：C₁₄H₂₅NO₃
• 分子量：255.35300
• 发布时间：2018-12-16 23:31:05
• 更新时间：2025-08-28 14:40:18

名称

• 中文名: (S)-3-(3-甲基丁酰基)吡咯烷-1-羧酸叔丁酯
• 英文名: tert-butyl (3S)-3-(3-methylbutanoyl)pyrrolidine-1-carboxylate
• 英文别名: (S)-1-Boc-3-(3-methylbutanoyl)pyrrolidine; (S)-3-(3-Methylbutanoyl)pyrrolidine-1-carboxylic acid tert-butyl ester; (S)-tert-butyl 3-(3-methylbutanoyl)pyrrolidine-1-carboxylate; (S)-tert-Butyl 3-(3-methylbutanoyl)pyrrolidine-1-carboxylate

物化性质

• 分子式: C₁₄H₂₅NO₃
• 分子量: 255.35300
• 精确质量: 255.18300
• PSA: 46.61000
• LogP: 2.79650

安全

• 海关编码: 2933990090

合成路线

1204677-53-1 926-62-5 ~99% 1251570-77-0

文献：Eli Lilly and Company Patent: US2010/261762 A1, 2010 ; Location in patent: Page/Page column 5-6 ;

1204677-53-1 5674-02-2 ~94% 1251570-77-0

文献：Dreyfus, Nicolas; Myers, Jason K.; Badescu, Valentina O.; De Frutos, Oscar; De La Puente, Maria Luz; Ding, Chunjin; Filla, Sandra A.; Fynboe, Karsten; Gernert, Douglas L.; Heinz, Beverly A.; Hemrick-Luecke, Susan K.; Johnson, Kirk W.; Johnson, Michael P.; Lopez, Pilar; Love, Patrick L.; Martin, Laura J.; Masquelin, Thierry; McCoy, Michael J.; Mendiola, Javier; Morrow, Denise; Muhlhauser, Mark; Pascual, Gustavo; Perun, Thomas J.; Pfeifer, Lance A.; Phebus, Lee A.; Richards, Simon J.; Rincon, Juan Antonio; Seest, Eric P.; Shah, Jikesh; Shaojuan, Jia; Simmons, Rosa Maria A.; Stephenson, Gregory A.; Tromiczak, Eric G.; Thompson, Linda K.; Walter, Magnus W.; Weber, Wayne W.; Zarrinmayeh, Hamideh; Thomas, Craig E.; Joshi, Elizabeth; Iyengar, Smriti; Johansson, Anette M. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 560 - 564

122684-33-7 ~% 1251570-77-0

文献：Dreyfus, Nicolas; Myers, Jason K.; Badescu, Valentina O.; De Frutos, Oscar; De La Puente, Maria Luz; Ding, Chunjin; Filla, Sandra A.; Fynboe, Karsten; Gernert, Douglas L.; Heinz, Beverly A.; Hemrick-Luecke, Susan K.; Johnson, Kirk W.; Johnson, Michael P.; Lopez, Pilar; Love, Patrick L.; Martin, Laura J.; Masquelin, Thierry; McCoy, Michael J.; Mendiola, Javier; Morrow, Denise; Muhlhauser, Mark; Pascual, Gustavo; Perun, Thomas J.; Pfeifer, Lance A.; Phebus, Lee A.; Richards, Simon J.; Rincon, Juan Antonio; Seest, Eric P.; Shah, Jikesh; Shaojuan, Jia; Simmons, Rosa Maria A.; Stephenson, Gregory A.; Tromiczak, Eric G.; Thompson, Linda K.; Walter, Magnus W.; Weber, Wayne W.; Zarrinmayeh, Hamideh; Thomas, Craig E.; Joshi, Elizabeth; Iyengar, Smriti; Johansson, Anette M. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 560 - 564

313706-15-9 ~% 1251570-77-0

文献：Dreyfus, Nicolas; Myers, Jason K.; Badescu, Valentina O.; De Frutos, Oscar; De La Puente, Maria Luz; Ding, Chunjin; Filla, Sandra A.; Fynboe, Karsten; Gernert, Douglas L.; Heinz, Beverly A.; Hemrick-Luecke, Susan K.; Johnson, Kirk W.; Johnson, Michael P.; Lopez, Pilar; Love, Patrick L.; Martin, Laura J.; Masquelin, Thierry; McCoy, Michael J.; Mendiola, Javier; Morrow, Denise; Muhlhauser, Mark; Pascual, Gustavo; Perun, Thomas J.; Pfeifer, Lance A.; Phebus, Lee A.; Richards, Simon J.; Rincon, Juan Antonio; Seest, Eric P.; Shah, Jikesh; Shaojuan, Jia; Simmons, Rosa Maria A.; Stephenson, Gregory A.; Tromiczak, Eric G.; Thompson, Linda K.; Walter, Magnus W.; Weber, Wayne W.; Zarrinmayeh, Hamideh; Thomas, Craig E.; Joshi, Elizabeth; Iyengar, Smriti; Johansson, Anette M. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 560 - 564

140148-70-5 ~% 1251570-77-0

文献：Dreyfus, Nicolas; Myers, Jason K.; Badescu, Valentina O.; De Frutos, Oscar; De La Puente, Maria Luz; Ding, Chunjin; Filla, Sandra A.; Fynboe, Karsten; Gernert, Douglas L.; Heinz, Beverly A.; Hemrick-Luecke, Susan K.; Johnson, Kirk W.; Johnson, Michael P.; Lopez, Pilar; Love, Patrick L.; Martin, Laura J.; Masquelin, Thierry; McCoy, Michael J.; Mendiola, Javier; Morrow, Denise; Muhlhauser, Mark; Pascual, Gustavo; Perun, Thomas J.; Pfeifer, Lance A.; Phebus, Lee A.; Richards, Simon J.; Rincon, Juan Antonio; Seest, Eric P.; Shah, Jikesh; Shaojuan, Jia; Simmons, Rosa Maria A.; Stephenson, Gregory A.; Tromiczak, Eric G.; Thompson, Linda K.; Walter, Magnus W.; Weber, Wayne W.; Zarrinmayeh, Hamideh; Thomas, Craig E.; Joshi, Elizabeth; Iyengar, Smriti; Johansson, Anette M. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 6 p. 560 - 564

上下游产品

上游产品  6
1204677-53-1 926-62-5 5674-02-2 122684-33-7
313706-15-9 140148-70-5
下游产品  1
1251570-88-3

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%