136401-69-9

• 常用中文名：(Z)-5-(4-(2-(5-乙基吡啶-2-基)乙氧基)亚苄基)噻唑烷-2,4-二酮
• 常用英文名：5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
• CAS号：136401-69-9
• 分子式：C₁₉H₁₈N₂O₃S
• 分子量：354.42300
• 发布时间：2017-05-26 08:42:08
• 更新时间：2025-08-26 12:24:04

名称

• 中文名: (Z)-5-(4-(2-(5-乙基吡啶-2-基)乙氧基)亚苄基)噻唑烷-2,4-二酮
• 英文名: 5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methylidene]-1,3-thiazolidine-2,4-dione
• 中文别名: 吡格列酮03; 吡格列酮杂质29(吡格列酮杂质B); (Z)-5-(4-(2-(5-乙基吡啶-2-基)乙氧基)亚苄基)噻唑烷-2,4-二酮 (吡格列酮杂质); 吡格列酮03B; (5Z)-吡格列酮杂质B; (5Z)-5-{4-[2-(5-乙基-2-吡啶基)乙氧基]亚苄基}-1,3-噻唑烷-2,4-二酮
• 英文别名: 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-, (5Z); Pioglitazone impurity B Didehydro Pioglitazone Impurity; 5-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzylidene}-thiazolidine-2,4-dione; 5-{4-[2-(5-ethyl-pyridin-2-yl)ethoxy]benzylidene}-2,4-thiazolidinedione; Pioglitazone Impurity 29 (Pioglitazone Impurity B); (Z)-5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione; (5Z)-Pioglitazone Impurity B; (Z)-5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzylidene)thiazolidine-2,4-dione (Pioglitazone Impurity); 2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methylene]-,(5E); Pioglitazone Impurity BQ: What is Pioglitazone Impurity B Q: What is the CAS Number of Pioglitazone Impurity B; 5-{4-[2-(5-ethyl-pyridin-2-yl)-ethoxy]-benzylidene}-2,4-thiazolidenedione; 5-<4-<2-(5-ethyl-2-pyridyl)ethoxy>benzylidene>-2,4-thiazolidinedione; Pioglitazone Impurity 29; 5-[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methenyl-2,4-thiazolidinedione; (Z)-5-{4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]BENZYLIDENE}-1,3-THIAZOLIDINE-2,4-DIONE; 5-[4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]-2-Imino-4-Thiazoldione

物化性质

• 密度: 1.302g/cm3
• 分子式: C₁₉H₁₈N₂O₃S
• 分子量: 354.42300
• 精确质量: 354.10400
• PSA: 97.08000
• LogP: 3.86530
• 折射率: 1.653

合成路线

2295-31-0 114393-97-4 ~99% 136401-69-9

文献：SANDOZ AG Patent: WO2005/49610 A1, 2005 ; Location in patent: Page/Page column 16 ;

110-89-4 2295-31-0 114393-97-4 ~62% 136401-69-9

文献：Takeda Chemical Industries, Ltd. Patent: EP257781 B1, 1991 ;

123-08-0 ~% 136401-69-9

文献：Mohanty, Sandeep; Reddy. G, Sandeep; Karmakar, Arun Chandra Letters in Organic Chemistry, 2014 , vol. 11, # 3 p. 197 - 202

5223-06-3 ~% 136401-69-9

文献：Momose; Meguro; Ikeda; Hatanaka; Oi; Sohda Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1440 - 1445

1194-02-1 ~% 136401-69-9

文献：Momose; Meguro; Ikeda; Hatanaka; Oi; Sohda Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1440 - 1445

136402-00-1 ~% 136401-69-9

文献：Momose; Meguro; Ikeda; Hatanaka; Oi; Sohda Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 6 p. 1440 - 1445

144809-27-8 ~% 136401-69-9

文献：Mohanty, Sandeep; Reddy. G, Sandeep; Karmakar, Arun Chandra Letters in Organic Chemistry, 2014 , vol. 11, # 3 p. 197 - 202

114393-97-4 ~% 136401-69-9

文献：Mohanty, Sandeep; Reddy. G, Sandeep; Karmakar, Arun Chandra Letters in Organic Chemistry, 2014 , vol. 11, # 3 p. 197 - 202

上下游产品

上游产品  7
2295-31-0 114393-97-4 110-89-4 123-08-0
5223-06-3 1194-02-1 144809-27-8
下游产品  2
136401-70-2 105355-27-9