1226781-87-8

• 常用中文名：tert-butyl {(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-yl}carbamate
• 常用英文名：tert-butyl {(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-yl}carbamate
• CAS号：1226781-87-8
• 分子式：C₂₂H₂₈F₂N₄O₅S
• 分子量：498.54300
• 发布时间：2016-11-27 02:34:36
• 更新时间：2025-08-22 19:51:54

名称

• 英文名: tert-butyl {(2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-yl}carbamate

物化性质

• 分子式: C₂₂H₂₈F₂N₄O₅S
• 分子量: 498.54300
• 精确质量: 498.17500
• PSA: 111.14000
• LogP: 4.11770

合成路线

6573-19-9 ~% 1226781-87-8

文献：Biftu, Tesfaye; Sinha-Roy, Ranabir; Chen, Ping; Qian, Xiaoxia; Feng, Dennis; Kuethe, Jeffrey T.; Scapin, Giovanna; Gao, Ying Duo; Yan, Youwei; Krueger, Davida; Bak, Annette; Eiermann, George; He, Jiafang; Cox, Jason; Hicks, Jacqueline; Lyons, Kathy; He, Huaibing; Salituro, Gino; Tong, Sharon; Patel, Sangita; Doss, George; Petrov, Aleksandr; Wu, Joseph; Xu, Shiyao Sherrie; Sewall, Charles; Zhang, Xiaoping; Zhang, Bei; Thornberry, Nancy A.; Weber, Ann E. Journal of Medicinal Chemistry, 2014 ,  vol. 57,  # 8  p. 3205 - 3212

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