185040-34-0

• 常用中文名：(4-(乙氨基)-2-(甲硫基)嘧啶-5-基)甲醇
• 常用英文名：(4-(ethylamino)-2-(Methylthio)pyrimidin-5-yl)Methanol
• CAS号：185040-34-0
• 分子式：C₈H₁₃N₃OS
• 分子量：199.27300
• 发布时间：2018-06-12 23:36:51
• 更新时间：2024-09-18 00:43:28

名称

• 中文名: (4-(乙基氨基)-2-(甲基硫代)嘧啶-5-基)甲醇
• 英文名: [4-(ethylamino)-2-methylsulfanylpyrimidin-5-yl]methanol
• 英文别名: 4-ethylamino-2-methylthio-5-pyrimidinemethanol; 4-ethylamino-2-methylthiopyrimidine-5-methanol

物化性质

• 密度: 1.24±0.1 g/cm3(Predicted)
• 沸点: 404.7±35.0 °C(Predicted)
• 熔点: 152-156 °C
• 分子式: C₈H₁₃N₃OS
• 分子量: 199.27300
• 精确质量: 199.07800
• PSA: 86.57000
• LogP: 0.54450
• 储存条件: 室温

合成路线

185040-33-9 ~92% 185040-34-0

文献：Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, Joann; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; San Pablo, Bong; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2255 - 2265

106475-47-2 ~35% 185040-34-0 211245-55-5

文献：Booth, Richard John; Chatterjee, Arindam; Malone, Thomas Charles Patent: US2004/224958 A1, 2004 ; US 20040224958 A1

5909-24-0 ~% 185040-34-0

文献：Goldstein, David M.; Soth, Michael; Gabriel, Tobias; Dewdney, Nolan; Kuglstatter, Andreas; Arzeno, Humberto; Chen, Jeffrey; Bingenheimer, William; Dalrymple, Stacie A.; Dunn, James; Farrell, Robert; Frauchiger, Sandra; La Fargue, Joann; Ghate, Manjiri; Graves, Bradford; Hill, Ronald J.; Li, Fujun; Litman, Renee; Loe, Brad; McIntosh, Joel; McWeeney, Daniel; Papp, Eva; Park, Jaehyeon; Reese, Harlan F.; Roberts, Richard T.; Rotstein, David; San Pablo, Bong; Sarma, Keshab; Stahl, Martin; Sung, Man-Ling; Suttman, Rebecca T.; Sjogren, Eric B.; Tan, Yunchou; Trejo, Alejandra; Welch, Mary; Weller, Paul; Wong, Brian R.; Zecic, Hasim Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2255 - 2265