70753-82-1

• 常用中文名：DL-Alanine (2,3-13C2)
• 常用英文名：DL-Alanine (2,3-13C2)
• CAS号：70753-82-1
• 分子式：C₃H₇NO₂
• 分子量：91.078
• 相关类别： 研究领域 代谢疾病
• 发布时间：2016-01-03 05:38:25
• 更新时间：2024-01-02 07:32:59
• DL-丙氨酸-13C2(DL-2-氨基丙酸-13C2)是13C标记的DL-丙氨酸。DL-丙氨酸是一种氨基酸,是L-和D-丙氨酸的外消旋化合物。DL-丙氨酸用作还原剂和封盖剂,与硝酸银水溶液一起用于生产纳米颗粒。DL-丙氨酸可用于Cu(Ⅱ)、Zn(Ⅱ)、Cd(11)等过渡金属螯合作用的研究。DL-丙氨酸是一种甜味剂,与甘氨酸和糖精钠一起分类。DL-丙氨酸在组织和肝脏之间的葡萄糖-丙氨酸循环中起着关键作用[1][2][3][4][5][6]。

名称

• 英文名: 2-aminopropanoic acid-C13
• 英文别名: (2,3-C)Alanine; Alanine-2,3-C

物化性质

• 密度: 1.2±0.1 g/cm3
• 熔点: 289ºC (dec.)(lit.)
• 分子式: C₃H₇NO₂
• 分子量: 91.078
• 精确质量: 91.054390
• PSA: 63.32000
• LogP: 0.11850
• 折射率: 1.460

生物活性

• 描述: DL-丙氨酸-13C2(DL-2-氨基丙酸-13C2)是13C标记的DL-丙氨酸。DL-丙氨酸是一种氨基酸,是L-和D-丙氨酸的外消旋化合物。DL-丙氨酸用作还原剂和封盖剂,与硝酸银水溶液一起用于生产纳米颗粒。DL-丙氨酸可用于Cu(Ⅱ)、Zn(Ⅱ)、Cd(11)等过渡金属螯合作用的研究。DL-丙氨酸是一种甜味剂,与甘氨酸和糖精钠一起分类。DL-丙氨酸在组织和肝脏之间的葡萄糖-丙氨酸循环中起着关键作用[1][2][3][4][5][6]。
• 相关类别:
  研究领域 >> 代谢疾病
• 体外研究: 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注[1]。
• 参考文献:

  [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

  [2]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

  [3]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

  [4]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

  [5]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

  [6]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

  [7]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

  [8]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

  [9]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

  [10]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

  [11]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.

  [12]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

  [13]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

  [14]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.

  [15]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

  [16]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.

  [17]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.

  [18]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.

  [19]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.

  [20]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

  [21]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

  [22]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

  [23]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.

  [24]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.

  [25]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.

安全

• 危险品运输编码: NONH for all modes of transport