34876-35-2

• 常用中文名：头孢氨苄杂质 D
• 常用英文名：3-Hydroxy-4-methyl-2(5H)-thiophenone
• CAS号：34876-35-2
• 分子式：C₅H₆O₂S
• 分子量：130.165
• 发布时间：2018-06-24 17:30:08
• 更新时间：2026-08-08 18:53:32

名称

• 中文名: 头孢氨苄杂质 D
• 英文名: 4-hydroxy-3-methyl-2H-thiophen-5-one
• 中文别名: 头孢拉定杂质F; 头孢羟氨苄杂质G; 头孢氨苄欧洲药典杂质D; 头孢拉定杂质F(头孢氨苄杂质D、头孢羟氨苄杂质G); 3-羟基-4-甲基噻吩酮; 头孢拉定杂质F头孢氨苄杂质D; 头孢氨苄杂质D对照品; 头孢拉定有关杂质 F; 头孢氨芐杂质; 头孢氨苄杂质4(头孢氨苄杂质D); 头孢羟氨苄杂质G(头孢拉定杂质F,头孢氨苄杂质D); 头孢羟氨苄杂质3; 头孢拉定杂质F对照品; 头孢氨苄杂质D(头孢拉定杂质F); 头孢拉定杂质F(头孢羟氨苄杂质G,头孢氨苄杂质D); 头孢羟氨苄杂质G(头孢氨苄杂质D、头孢拉定杂质F); 头孢氨苄杂质D(头孢拉定杂质F、头孢羟氨苄杂质G); 头孢氨苄杂质D、 头孢羟氨苄杂质G、头孢拉定杂质F (TBAB-D); 头孢拉定杂质6(头孢拉定杂质F); 3-羟基-4-甲基-2(5H)-噻吩酮; 头孢羟氨苄有关杂质 G; 头孢氨苄杂质D; 头孢氨芐杂质 G; 参见 C-479; 头孢氨苄有关杂质 D; 3-羟基-4-甲基噻吩-2(5H)-酮 (头孢拉定杂质); 头孢羟氨苄 杂质 G
• 英文别名: Chalexin Impurity D (Cefradine Impurity F); Cefradine Impurity F; Cefalexin Impurity D (Cefradine Impurity F, Cefadroxil Impurity G, Chalexin Related Compound D); Cefadroxil Impurity G; Chalexin Impurity D/Cefradine Impurity F/Cefadroxil Impurity G/3-hydroxy-4-methylthiophen-2(5H)-one; Chalexin Impurity D; Cefradine Impurity 6(Cefradine Impurity F); Cefalexin Impurity D（Cefradine Impurity F、Cefadroxil Impurity G）; Cefadroxil Impurity 2; Refer to C-479; Cefadroxil Impurity G (Chalexin Impurity D, Cefradine Impurity F); Cefadroxil Impurity G (Cefradine Impurity F, Chalexin Impurity D); Cefadroxil Impurity G/Cefradine Impurity F; 3-Hydroxy-4-Methyl-2(5H)-thiophenone; Cefradine EP Impurity D; Cefalexin Impurity D; Cefalexin Impurity 4 Impurity D); Cefalexin Impurity 4（Cefalexin Impurity D）; Cefadroxil Impurity 2（Cefadroxil Impurity G）; Cefradine impurity 4/Cefradine Impurity F/3-hydroxy-4-methylthiophen-2(5H)-one; 2(5H)-Thiophenone, 3-hydroxy-4-methyl; Chalexin Impurity D (Cefradine Impurity F, Cefadroxil Impurity G); 3-Hydroxy-4-methylthiophen-2(5H)-one; Cefradine Impurity F (Chalexin Impurity D, Cefadroxil Impurity G); Chalexin Impurity D、Cefadroxil Impurity G、Cefradine Impurity F (TBAB-D); 3-hydroxy-4-methyl-5H-thiophen-2-one; Cefradine Impurity F (Cefalexin Impurity D); Cefadroxil Impurity G（Cefradine Impurity F/Cefalexin Impurity D）; Cefalexin Impurity D (Cefradine Impurity F); Cefalexin-Imp-D; cefalexin Impurity G; UNII-82S555S2NY; Chalexin Related Compound D (3-Hydroxy-4-methylthiophen-2(5H)-one); Cefradine Impurity F (Cefadroxil Impurity G, Chalexin Impurity D); 3-Hydroxy-4-methylthiophen-2(5H)-one (Cefradine Impurity); Cefalexin Impurity D Control

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 305.9±42.0 °C at 760 mmHg
• 分子式: C₅H₆O₂S
• 分子量: 130.165
• 闪点: 138.8±27.9 °C
• 精确质量: 130.008850
• PSA: 62.60000
• LogP: 0.55
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.637

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

31461-05-9 ~% 34876-35-2

文献：Hendrix; Roets; Bervoets; Thomas; Pijcke; Busson; Janssen; Hoogmartens Archiv der Pharmazie, 1994 , vol. 327, # 4 p. 215 - 219

30959-67-2 ~% 34876-35-2

文献：Hendrix; Roets; Bervoets; Thomas; Pijcke; Busson; Janssen; Hoogmartens Archiv der Pharmazie, 1994 , vol. 327, # 4 p. 215 - 219

57872-62-5 ~% 34876-35-2

文献：Hendrix; Roets; Bervoets; Thomas; Pijcke; Busson; Janssen; Hoogmartens Archiv der Pharmazie, 1994 , vol. 327, # 4 p. 215 - 219

616-44-4 ~2% 34876-35-2

文献：Boyd, Derek R; Sharma, Narain D; Gunaratne, Nimal; Haughey, Simon A; Kennedy, Martina A; Malone, John F; Allen, Christopher C; Dalton, Howard Organic and biomolecular chemistry, 2003 , vol. 1, # 6 p. 984 - 994

50370-12-2 ~% 34876-35-2

文献：Hendrix; Roets; Roesems; Busson; Rozenski; Janssen; Hoogmartens Archiv der Pharmazie, 1994 , vol. 327, # 12 p. 805 - 807

15686-71-2 ~43% 34876-35-2

文献：Hendrix; Roets; Bervoets; Thomas; Pijcke; Busson; Janssen; Hoogmartens Archiv der Pharmazie, 1994 , vol. 327, # 4 p. 215 - 219

上下游产品

上游产品  3
15686-71-2 616-44-4 50370-12-2
下游产品  0