343788-69-2

• 常用中文名：4-氨基-4-甲基哌啶-1-甲酸叔丁酯
• 常用英文名：4-Amino-4-methyl-1-piperidinecarboxylic acid tert-butyl ester
• CAS号：343788-69-2
• 分子式：C₁₁H₂₂N₂O₂
• 分子量：214.305
• 发布时间：2018-07-14 15:37:18
• 更新时间：2026-06-30 11:55:40

名称

• 中文名: 4-氨基-4-甲基哌啶-1-甲酸叔丁酯
• 英文名: tert-butyl 4-amino-4-methylpiperidine-1-carboxylate
• 中文别名: 4-氨基-4-甲基六氢吡啶-1-甲酸丁酯; 1-BOC-4-甲基-4-氨基哌啶; N-BOC-4-氨基-4-甲基哌啶; 1-BOC-4-氨基-4-甲基哌啶; N-BOC-4-甲基-4-氨基哌啶; 4-氨基-1-N-叔丁氧基羰基-4-甲基哌啶; 4-氨基-4-甲基哌啶-1-羧酸叔丁酯
• 英文别名: 4-Amino-4-Methyl-1-piperidinecboxylic acid tert-butyl ester; butyl 4-amino-4-Methylpiperidine-1-cboxylate; TERT-BUTYL-4-AMINO-4-METHYLPIP; 1,1-dimethylethyl 4-amino-4-methyl-1-piperidinecarboxylate; 4-amino-4-methyl-piperidine-1-carboxylic acid tert-butyl ester; 4-AMINO-4-METHYL-1-BOC-PIPERIDINE; 4-AMINO-4-METHYL-N-BOC-PIPERIDINE; 4-Amino-1-Boc-4-methylpip; 4-AMINO-1-N-BUTOXYCBONYL-4-METHYL-PIPERIDINE; 1-BOC-4-AMINO-4-METHYL PIPERADINE; N-Boc-4-amino-4-methylpiperidine; 4-AMINO-1-N-BUTOXYCARBONYL-4-METHYL-PIPERIDINE; 4-Amino-4-methyl-1-Boc-piperidine; 1-Boc-4-Amino-4-methylpiperidine; tert-butyl-4-amino-4-methylpiperidine-1-carboxylate; 4-Amino-1-Boc-4-methylpiperidine; TERT-BUTYL 4-AMINO-4-METHYLPIPERIDINE-1-CBOXYLATE; N1-Boc-4-amino-4-methylpiperidine; 1-Boc-4-Amino-4-Methylpiperidine; 4-AMINO-1-N-TERT-BUTYLOXYCBONYL-4-METHYL-PIPERIDINE; 4-Amino-1-N-boc-4-methyl-piperidine; N'-butoxycarbonyl-4-methyl-4-aminopiperidine; 4-amino-1-n-tert-butyloxycarbonyl-4-methyl-piperidine; 1-Piperidinecboxylic acid, 4-amino-4-Methyl-, 1,1-diMethylethyl ester; 1-(tert-Butoxycbonyl)-4-amino-4-methylpiperidine

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 283.0±33.0 °C at 760 mmHg
• 分子式: C₁₁H₂₂N₂O₂
• 分子量: 214.305
• 闪点: 125.0±25.4 °C
• 精确质量: 214.168121
• PSA: 55.56000
• LogP: 1.21
• 外观性状: 固体;White to Light yellow powder to lump
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.478
• 储存条件: 0-10°C;存放于惰性气体之中;避免空气,加热

安全

• 海关编码: 2933399090

合成路线

236406-14-7 ~93% 343788-69-2

文献：PURDUE PHARMA L.P.; SHIONOGI and CO., LTD. Patent: WO2008/89201 A2, 2008 ; Location in patent: Page/Page column 234-235 ; WO 2008/089201 A2

163271-06-5 24424-99-5 ~97% 343788-69-2

文献：GLAXO GROUP LIMITED Patent: WO2008/119718 A1, 2008 ; Location in patent: Page/Page column 45 ; WO 2008/119718 A1

872850-48-1 ~99% 343788-69-2

文献：VERTEX PHARMACEUTICALS INCORPORATED Patent: US2010/137305 A1, 2010 ; Location in patent: Page/Page column 37 ;

189321-63-9 ~% 343788-69-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

343788-67-0 ~% 343788-69-2

文献：Organic Process Research and Development, , vol. 13, # 6 p. 1145 - 1155

142851-03-4 ~% 343788-69-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

189442-87-3 ~% 343788-69-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 14 p. 3675 - 3678

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%