1207961-61-2

• 常用中文名：2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
• 常用英文名：2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester
• CAS号：1207961-61-2
• 分子式：C₂₃H₂₆ClFN₆O₃
• 分子量：488.94200
• 发布时间：2017-04-09 15:02:51
• 更新时间：2024-02-09 18:12:02

名称

• 英文名: 2-amino-4-{4-chloro-2-[2-(4-fluoro-pyrazol-1-yl)-ethoxy]-6-methyl-phenyl}-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester

物化性质

• 分子式: C₂₃H₂₆ClFN₆O₃
• 分子量: 488.94200
• 精确质量: 488.17400
• PSA: 108.39000
• LogP: 4.87200

合成路线

1207961-58-7 1207961-48-5 ~62% 1207961-61-2

文献：Pfizer Inc Patent:   US2010/41681 A1, 2010 ; Location in patent: Page/Page column 30 ;

1207961-49-6 ~% 1207961-61-2

文献：Zehnder, Luke; Bennett, Michael; Meng, Jerry; Huang, Buwen; Ninkovic, Sacha; Wang, Fen; Braganza, John; Tatlock, John; Jewell, Tanya; Zhou, Joe Zhongxiang; Burke, Ben; Wang, Jeff; Maegley, Karen; Mehta, Pramod P.; Yin, Min-Jean; Gajiwala, Ketan S.; Hickey, Michael J.; Yamazaki, Shinji; Smith, Evan; Kang, Ping; Sistla, Anand; Dovalsantos, Elena; Gehring, Michael R.; Kania, Robert; Wythes, Martin; Kung, Pei-Pei Journal of Medicinal Chemistry, 2011 ,  vol. 54,  # 9  p. 3368 - 3385

上下游产品

上游产品  3
1207961-58-7 1207961-48-5 1207961-49-6
下游产品  2
1207961-33-8 1207961-60-1