103343-47-1

• 常用中文名：3-氨基-5-苯基-1H-苯并[E][1,4]二氮杂卓-2(3H)-酮
• 常用英文名：3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
• CAS号：103343-47-1
• 分子式：C₁₅H₁₃N₃O
• 分子量：251.283
• 发布时间：2018-12-12 22:55:30
• 更新时间：2024-01-10 12:08:40

名称

• 中文名: 3-氨基-5-苯基-1,3-二氢-2H-1,4-苯并二氮杂革-2-酮
• 英文名: 3-amino-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
• 英文别名: 3-amino-2,3-dihydro-5-phenyl-1H-1,4-benzodiazepin-2-one; 3-(RS)-Amino-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one; 3-Amino-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine; 3-amino-5-phenyl-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one; 2H-1,4-Benzodiazepin-2-one, 3-amino-1,3-dihydro-5-phenyl-; 3-Amino-5-phenyl-1H-benzo[e][1,4]diazepin-2(3H)-one; 3-Amino-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 3-amino-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one; (3RS)-1,3-dihydro-3-amino-5-phenyl-2H-1,4-benzodiazepine-2-one

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 456.7±45.0 °C at 760 mmHg
• 分子式: C₁₅H₁₃N₃O
• 分子量: 251.283
• 闪点: 230.0±28.7 °C
• 精确质量: 251.105865
• PSA: 67.48000
• LogP: 1.45
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.684
• 储存条件: 2-8°C， 避光保存， 惰性气氛

安全

• 海关编码: 2933990090

合成路线

108895-98-3 ~88% 103343-47-1

文献：Sherrill; Sugg Journal of Organic Chemistry, 1995 , vol. 60, # 3 p. 730 - 734

108895-97-2 ~% 103343-47-1

文献：Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

2835-77-0 ~% 103343-47-1

文献：Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

106849-44-9 ~% 103343-47-1

文献：Bock, Mark G.; DiPardo, Robert M.; Evans, Ben E.; Rittle, Kenneth E.; Veber, Daniel F.; et al. Journal of Organic Chemistry, 1987 , vol. 52, # 15 p. 3232 - 3239

96042-30-7 108895-98-3 ~% 103343-47-1

文献：Glaxo Wellcome Inc. Patent: US5795887 A1, 1998 ; US 5795887 A

100-47-0 ~% 103343-47-1

文献：Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

74497-02-2 ~% 103343-47-1

文献：Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

2898-08-0 ~% 103343-47-1

文献：Pascal, Yves; Andrianjara, Charles R.; Auclair, Eric; Avenel, Nadine; Bertin, Bernadette; Calvet, Alain; Feru, Frederic; Lardon, Sophie; Moodley, Indres; Ouagued, Malika; Payne, Adrian; Pruniaux, Marie-Pierre; Szilagyi, Corinne Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 1 p. 35 - 38

821800-04-8 ~% 103343-47-1

文献：Micale, Nicola; Vairagoundar, Rajendran; Yakovlev, Alexander G.; Kozikowski, Alan P. Journal of Medicinal Chemistry, 2004 , vol. 47, # 26 p. 6455 - 6458

上下游产品

上游产品  8
108895-98-3 108895-97-2 2835-77-0 106849-44-9
96042-30-7 100-47-0 2898-08-0 821800-04-8
下游产品  4
103343-65-3 253135-95-4 796038-21-6 70890-53-8

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%