590-31-8

• 常用中文名：美普溴铵
• 常用英文名：Meprochol
• CAS号：590-31-8
• 分子式：C₇H₁₆BrNO
• 分子量：210.11200
• 发布时间：2018-09-20 14:00:45
• 更新时间：2024-01-10 12:43:20

名称

• 中文名: 美普溴铵
• 英文名: 2-methoxyprop-2-enyl(trimethyl)azanium,bromide
• 英文别名: (2-Methoxy-allyl)-trimethyl-ammonium,Bromid; AMMONIUM,(2-METHOXYALLYL)TRIMETHYL-,BROMIDE; (2-methoxy-allyl)-trimethyl-ammonium,bromide; Esmodil; Meprochol; (2-Methoxyprop-2-enyl)trimethylammonium bromide; Esmodyl; UNII-7K2B1728PB; Meprochol [BAN]; 2-Methoxy-N,N,N-trimethyl-2-propen-1-aminium bromide

物化性质

• 分子式: C₇H₁₆BrNO
• 分子量: 210.11200
• 精确质量: 209.04200
• PSA: 9.23000

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BR7167000 CHEMICAL NAME : Ammonium, (2-methoxyallyl)trimethyl-, bromide CAS REGISTRY NUMBER : 590-31-8 LAST UPDATED : 199206 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C7-H16-N-O.Br MOLECULAR WEIGHT : 210.15 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Cardiac - pulse rate Gastrointestinal - changes in structure or function of salivary glands REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,397,1948 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Cardiac - pulse rate Gastrointestinal - changes in structure or function of salivary glands REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,397,1948 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Cardiac - pulse rate Gastrointestinal - changes in structure or function of salivary glands REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,397,1948 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Cardiac - pulse rate Gastrointestinal - changes in structure or function of salivary glands REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,397,1948

合成路线

32730-64-6 124-40-3 ~% 590-31-8

文献：Winthrop Chem.Co. Patent: US2119802 , 1934 ; Full Text Show Details I.G.Farbenind. Patent: DE614462 , 1933 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 499 Full Text Show Details I.G.Farbenind. Patent: FR782819 , 1934 ;

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