25150-61-2

• 常用中文名：吡咯烷盐酸盐
• 常用英文名：Pyrrolidine,hydrochloride (1:1)
• CAS号：25150-61-2
• 分子式：C₄H₁₀ClN
• 分子量：107.58200
• 发布时间：2017-10-31 09:21:15
• 更新时间：2024-01-02 07:43:11

名称

• 中文名: 吡咯烷盐酸盐
• 英文名: pyrrolidine,hydrochloride
• 英文别名: pyrrolidinium chloride; pyrrolidine hydrochloride; pyrrolidinium hydrochloride; pyrrolidin-1-ium chloride; pyrrolidine hydrochloride salt; pyrrolidin hydrochloride; axetidine hydrochloride

物化性质

• 密度: 0.839g/cm3
• 沸点: 89.5ºC at 760mmHg
• 熔点: -57.79ºC
• 分子式: C₄H₁₀ClN
• 分子量: 107.58200
• 闪点: 2.8ºC
• 精确质量: 107.05000
• PSA: 12.03000
• LogP: 1.50060
• 蒸汽压: 58.6mmHg at 25°C
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UY1300000 CHEMICAL NAME : Pyrrolidine, hydrochloride CAS REGISTRY NUMBER : 25150-61-2 LAST UPDATED : 199012 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C4-H9-N.Cl-H MOLECULAR WEIGHT : 107.60 WISWESSER LINE NOTATION : T5MTJ &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 241 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,321,1970

合成路线

123-75-1 ~96% 25150-61-2

文献：PFIZER PRODUCTS INC. Patent: WO2007/49123 A1, 2007 ; Location in patent: Page/Page column 31 ; WO 2007/049123 A1

110-61-2 ~21% 25150-61-2 16011-90-8

文献：Laval, Stephane; Dayoub, Wissam; Pehlivan, Leyla; Metay, Estelle; Favre-Reguillon, Alain; Delbrayelle, Dominique; Mignani, Gerard; Lemaire, Marc Tetrahedron, 2014 , vol. 70, # 4 p. 975 - 983

55552-54-0 ~89% 25150-61-2

文献：Cheng, Chen; Brookhart, Maurice Journal of the American Chemical Society, 2012 , vol. 134, # 28 p. 11304 - 11307

113738-20-8 ~% 25150-61-2

文献：Jego, J. M.; Carboni, B.; Vaultier, M. Bulletin de la Societe Chimique de France, 1992 , # 6 p. 554 - 565

61632-72-2 ~% 25150-61-2

文献：Jego, Jean Michel; Carboni, Bertrand; Vaultier, Michel; Carrie, Robert Journal of the Chemical Society, Chemical Communications, 1989 , # 2 p. 142 - 143

123-75-1 35509-87-6 ~% 18370-19-9 25150-61-2

文献：Dworniczak, Miroslaw; Jarczewski, Arnold Acta Chimica Hungarica, 1989 , vol. 126, # 5 p. 599 - 604

上下游产品

上游产品  6
123-75-1 110-61-2 55552-54-0 113738-20-8
61632-72-2 35509-87-6
下游产品  10
493-92-5 40398-36-5 31466-31-6 1689-02-7
14552-00-2 108-95-2 296264-94-3 833-86-3
87849-03-4 91470-89-2