209861-00-7

• 常用中文名：2H-环戊并[B]呋喃-2-酮,5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-丁烯-1-基]六氢-,(3AR,4R,5R,6AS)-(...)
• 常用英文名：(3AR,4R,5R,6AS)-4-((E)-3,3-DIFLUORO-4-PHENOXYBUT-1-EN-1-YL)-2-OXOHEXAHYDRO-2H-CYCLOPENTA[B]FURAN-5-YL BENZOATE
• CAS号：209861-00-7
• 分子式：C₂₄H₂₂F₂O₅
• 分子量：428.425
• 发布时间：2016-08-20 01:33:10
• 更新时间：2026-07-12 19:54:00

名称

• 中文名: 2H-环戊并[B]呋喃-2-酮,5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-丁烯-1-基]六氢-,(3AR,4R,5R,6AS)-(...)
• 英文名: [(3aR,4R,5R,6aS)-4-(3,3-difluoro-4-phenoxybut-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
• 中文别名: 前列腺素杂质38; 3,3-二氟-4-苯氧基-丁烯; 他氟前列素杂质22; (3,4R,5R,6AS)-5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-1-丁烯-1-基]六氢2H-环戊烷并[B]呋喃-2-酮; 2H-环戊并[B]呋喃-2-酮,5-(苯甲酰氧基); (3,4R,5R,6AS)- 5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-丁烯-1-基]六氢-2H-环戊并[B]呋喃-2-酮; 他氟前列素中间体1; 他氟前列素杂质29; (3,4R,5R,6AS)-5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-1-丁烯基]六氢-2H-环戊二烯并[B]呋喃-2-酮; 批发209-7; (3,4R,5R,6AS)-4-((E)-3,3-二氟-4-苯氧基丁-1-烯-1-基)-2-氧代六氢-2H-环戊二烯并[B]呋喃-5-基苯甲酸酯; 中间体209-7; 2H-环戊并[B]呋喃-2-酮,5-(苯甲酰氧基)-4-[(1E)-3,3-二氟-4-苯氧基-丁烯-1-基]六氢-,(3,4R,5R,6AS)-(...); 拉坦前列腺素杂质21
• 英文别名: (3aR,4R,5R,6aS)-4-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate; Tafluprost int; (3,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cy; 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-, (3,4R,5R,6aS); (1S,5R,6R,7R)-2-oxa-7-benzoyloxy-6-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl]bicyclo[3.3.0]octan-3-one; (3,4R,5R,6aS)-5-(Benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl]hexahydro-2H-cyclopenta[b]furan-2-one; (3,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]fur; (3,4R,5R,6aS)-5-(benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-on; Tafluprost Impurity 29; Tafluprost Intermediate; Prostaglandin Impurity 38; 2H-Cyclopenta[b]furan-2-one,5-(benzoyloxy)-4-[(1E)-3,3-diflu; (3aR,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate; 2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-butenyl]hexahydro-, (3,4R,5R,6aS); (3,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan; (3,4R,5R,6aS)-4-((E)-3,3-difluoro-4-phenoxybutan-1-en-1-yl)-hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl benzoate; (3,4R,5R,6aS)-5-(benzoyloxy)-4-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]hexahydro-2H-Cyclopenta[b]furan-2-one; Latanoprost Impurity 21; (3,4R,5R,6aS)-4-((E)-3,3-Difluoro-4-phenoxybut-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate; [(3,4R,5R,6aS)-4-(3,3-difluoro-4-phenoxybut-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate; TF-BF

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 588.3±50.0 °C at 760 mmHg
• 分子式: C₂₄H₂₂F₂O₅
• 分子量: 428.425
• 闪点: 298.1±25.0 °C
• 精确质量: 428.143524
• PSA: 61.83000
• LogP: 4.29
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.579

合成路线

51638-91-6 ~80% 209861-00-7

文献：DR.REDDYS LABORATORIES LIMITED; JACKSON, Mark P Patent: WO2013/118058 A1, 2013 ; Location in patent: Page/Page column 8 ;

40665-68-7 ~% 209861-00-7

文献：DR.REDDYS LABORATORIES LIMITED; JACKSON, Mark P Patent: WO2013/118058 A1, 2013 ;

39746-01-5 ~% 209861-00-7

文献：DR.REDDYS LABORATORIES LIMITED; JACKSON, Mark P Patent: WO2013/118058 A1, 2013 ;

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