34245-49-3

• 常用中文名：9-((3aR,4R,6R,6aR)-2,2-二甲基-6-((甲基氨基)甲基)四氢呋喃[3,4-d][1,3]二氧戊环-4-基)-9H-嘌呤-6-胺
• 常用英文名：9-((3AR,4R,6R,6AR)-2,2-DIMETHYL-6-((METHYLAMINO)METHYL)TETRAHYDROFURO[3,4-D][1,3]DIOXOL-4-YL)-9H-PURIN-6-AMINE
• CAS号：34245-49-3
• 分子式：C₁₄H₂₀N₆O₃
• 分子量：320.34700
• 发布时间：2018-11-22 13:28:00
• 更新时间：2025-08-26 17:04:40

名称

• 中文名: 5-脱氧-5-(甲基氨基)-2,3-O-(1-甲基亚乙基)-腺苷酸
• 英文名: 9-[(3aR,4R,6R,6aR)-2,2-dimethyl-6-(methylaminomethyl)-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl]purin-6-amine
• 英文别名: 5'-methylamino-O2',O3'-isopropylidene-5'-deoxy-adenosine; 9-((3aR,4R,6R,6aR)-2,2-Dimethyl-6-((methylamino)methyl)tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-amine; 5'-deoxy-2',3'-O-methylethylidene-5'-methylaminoadenosine; 5'-deoxy-5'-methylamino-2',3'-isopropylideneadenosine; 5'-deoxy-5'-methylamino-2',3'-O,O-(1-methylethylidene)adenosine

物化性质

• 分子式: C₁₄H₂₀N₆O₃
• 分子量: 320.34700
• 精确质量: 320.16000
• PSA: 109.34000
• LogP: 1.01750
• 外观性状: 白色至灰白色固体
• 储存条件: 2-8°C， 避光， 惰性气体

合成路线

1194995-79-3 ~83% 34245-49-3

文献：Joce, Catherine; Caryl, Jamie; Stockley, Peter G.; Warriner, Stuart; Nelson, Adam Organic and Biomolecular Chemistry, 2009 , vol. 7, # 4 p. 635 - 638

68179-90-8 74-89-5 ~% 34245-49-3

文献：McCloskey, Diane E.; Bale, Shridhar; Secrist III, John A.; Tiwari, Anita; Moss III, Thomas H.; Valiyaveettil, Jacob; Brooks, Wesley H.; Guida, Wayne C.; Pegg, Anthony E.; Ealick, Steven E. Journal of Medicinal Chemistry, 2009 , vol. 52, # 5 p. 1388 - 1407

5605-63-0 74-89-5 ~85% 34245-49-3

文献：Davis, Michael; Dudman, Nicholas P. B.; White, Hume F. Australian Journal of Chemistry, 1983 , vol. 36, # 8 p. 1623 - 1627

362-75-4 ~% 34245-49-3

文献：Marasco Jr., Canio J.; Kramer, Debora L.; Miller, John; Porter, Carl W.; Bacchi, Cyrus J.; Rattendi, Donna; Kucera, Louis; Iyer, Nathan; Bernacki, Ralph; Pera, Paula; Sufrin, Janice R. Journal of Medicinal Chemistry, 2002 , vol. 45, # 23 p. 5112 - 5122

24514-56-5 74-89-5 ~% 34245-49-3

文献：Marasco Jr., Canio J.; Kramer, Debora L.; Miller, John; Porter, Carl W.; Bacchi, Cyrus J.; Rattendi, Donna; Kucera, Louis; Iyer, Nathan; Bernacki, Ralph; Pera, Paula; Sufrin, Janice R. Journal of Medicinal Chemistry, 2002 , vol. 45, # 23 p. 5112 - 5122

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