149289-29-2

• 常用中文名：N,N,O-Tridesmethylvenlafaxine
• 常用英文名：N,N,O-Tridesmethylvenlafaxine
• CAS号：149289-29-2
• 分子式：C₁₄H₂₁NO₂
• 分子量：235.32200
• 相关类别： 研究领域 代谢疾病
• 发布时间：2016-07-20 02:34:25
• 更新时间：2026-07-01 17:54:30
• N,N,O-Tridesmethylvenlafaxine 是一种内源性代谢产物。

名称

• 中文名: O-去甲基-N,N-二甲基文拉法辛
• 英文名: 4-[2-Amino-1-(1-hydroxycyclohexyl)ethyl]phenol
• 中文别名: 去甲文拉法辛杂质I-4; 文拉法辛杂质23; 氨基-1-(4-羟苯基)乙基环己醇; O-去甲基-N,N-二去甲基文拉法辛; 4-(2-氨基-1-(1-羟基环己基)乙基)苯酚; N,N,O-Tridesmethylvenlafaxine #天然产物 HY-W049735; N,N-二去甲基-O-去甲基文拉法辛; 去甲文拉法辛杂质6; 文法拉辛杂质; 1-[2-氨基-1-(4-羟基苯基)乙基]环己醇
• 英文别名: O-desmethyl-N,N-didesmethylvenlafaxine; 1-(thiophen-2-yl)propan-1-amine; Tridesmethylvenlafaxine; Effexor Impurity 25; N,N,O-Tridesmethylvenlafaxine, 10 mM in DMSO; 1-thiophen-2-yl-propylamine; O,N,N tri desmethyl Venlafaxine; |A-ethyl-2-thenylamine; Desvenlafaxine N,N-Didesmethyl Imp; N,N-Didesmethyl-O-desmethyl Venlafaxine; 2-(1-Aminopropyl)-thiophen; Inhibitor,N,N,O-Tridesmethylvenlafaxine,inhibit,Endogenous Metabolite,N,N,OTridesmethylvenlafaxine,N,N,O Tridesmethylvenlafaxine; O-desmethyl-N,N-dimethyl venlafaxine; 1-[2]thienyl-propylamine; Desvenlafaxine Impurity 6; 1-(thien-2-yl)-propylamine; Desmethylvenlafaxine Impurity 6; Phenol, 4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]; 1-[2-amino-1-(4-hydroxyphenyl)ethyl]-cyclohexanol; N,N-Didesmethyldesvenlafaxine; tridesmethylvenlafaxine; D,L-N,N-DidesMethyl-O-desMethyl Venlafaxine; O-Desmethyl-N,N-didesmethylvenlafaxine; 4-[2-amino-1-(1-hydroxycyclohexyl)ethyl]phenol; 1-[2]Thienyl-propylamin

物化性质

• 分子式: C₁₄H₂₁NO₂
• 分子量: 235.32200
• 精确质量: 235.15700
• PSA: 66.48000
• LogP: 2.83000
• 储存条件: 2-8°C

生物活性

• 描述: N,N,O-Tridesmethylvenlafaxine 是一种内源性代谢产物。
• 相关类别:
  研究领域 >> 代谢疾病

合成路线

130198-05-9 ~91% 149289-29-2

文献：Niddam-Hildesheim, Valarie; Nidam, Tamar; Vollerner, Yuri; Adler, Miri; Kravitz, Miri; Shachan-tov, Sharona Patent: US2009/234020 A1, 2009 ; Location in patent: Page/Page column 6 ;

93413-77-5 ~91% 149289-29-2

文献：MEDICHEM, S.A. Patent: US2010/121108 A1, 2010 ; Location in patent: Page/Page column 3 ;

26960-77-0 93413-77-5 ~52% 149289-29-2 3698-89-3 详细

文献：Niddam-Hildesheim, Valerie; Shenkar, Natalia; Shachan-Tov, Sharona Patent: US2008/139849 A1, 2008 ; Location in patent: Page/Page column 5 ;

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