159831-73-9

• 常用中文名：4-amino-7-chloro-6-fluorocinnoline-3-carboxylic acid
• 常用英文名：4-amino-7-chloro-6-fluorocinnoline-3-carboxylic acid
• CAS号：159831-73-9
• 分子式：C₉H₅ClFN₃O₂
• 分子量：241.60600
• 发布时间：2017-07-27 21:42:02
• 更新时间：2024-01-02 18:53:28

名称

• 英文名: 4-amino-7-chloro-6-fluorocinnoline-3-carboxylic acid
• 英文别名: 3-Cinnolinecarboxylic acid,4-amino-7-chloro-6-fluoro-,hydrate; 4-Amino-7-chloro-6-fluoro-3-cinnolinecarboxylic acid hydrate; 4-Amino-6-fluoro-7-chlorocinnoline-3-carboxylicacid

物化性质

• 密度: 1.713g/cm3
• 沸点: 464.6ºC at 760 mmHg
• 分子式: C₉H₅ClFN₃O₂
• 分子量: 241.60600
• 闪点: 234.8ºC
• 精确质量: 241.00500
• PSA: 89.10000
• LogP: 2.28390
• 蒸汽压: 1.98E-09mmHg at 25°C
• 折射率: 1.731

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GE3623156 CHEMICAL NAME : 3-Cinnolinecarboxylic acid, 4-amino-7-chloro-6-fluoro-, hydrate CAS REGISTRY NUMBER : 159831-73-9 LAST UPDATED : 199603 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H5-Cl-F-N3-O2.H2-O MOLECULAR WEIGHT : 259.64 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 49,884,1994

合成路线

159831-72-8 ~81% 159831-73-9

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

367-21-5 ~% 159831-73-9

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889

161373-26-8 ~% 159831-73-9

文献：Stanczak; Kwapiszewski; Lewgowd; Ochocki; Szadowska; Pakulska; Glowka Pharmazie, 1994 , vol. 49, # 12 p. 884 - 889