34375-78-5

• 常用中文名：1,3-dimethyl-4,5-dihydropyrazolo[3,4-b][1,4]benzoxazepine,hydrochloride
• 常用英文名：1,3-dimethyl-4,5-dihydropyrazolo[3,4-b][1,4]benzoxazepine,hydrochloride
• CAS号：34375-78-5
• 分子式：C₁₂H₁₄ClN₃O
• 分子量：251.71200
• 发布时间：2016-11-15 00:30:15
• 更新时间：2024-01-08 20:54:21

名称

• 英文名: 1,3-dimethyl-4,5-dihydropyrazolo[3,4-b][1,4]benzoxazepine,hydrochloride

物化性质

• 沸点: 406.6ºC at 760 mmHg
• 分子式: C₁₂H₁₄ClN₃O
• 分子量: 251.71200
• 闪点: 199.7ºC
• 精确质量: 251.08300
• PSA: 39.08000
• LogP: 3.38630

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UQ9880000 CHEMICAL NAME : 1H-Pyrazolo(3,4-b)(1,4)-benzoxazepine, 4,5-dihydro-1,3-dimethyl-, hydrochloride CAS REGISTRY NUMBER : 34375-78-5 LAST UPDATED : 199012 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C12-H13-N3-O.Cl-H MOLECULAR WEIGHT : 251.74 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1360 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 202,119,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1276 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 202,119,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 465 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 202,119,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 220 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 202,119,1973