12111-24-9

• 常用中文名：喷替酸钙钠
• 常用英文名：calcium trisodium pentetate
• CAS号：12111-24-9
• 分子式：C₁₄H₁₈CaN₃Na₃O₁₀
• 分子量：497.35400
• 相关类别： 原料药 专科用药 解毒药
• 发布时间：2018-06-13 19:45:15
• 更新时间：2026-07-14 10:41:12

名称

• 中文名: 喷替酸钙钠
• 英文名: calcium trisodium pentetate
• 中文别名: 喷替酸钙钠 标准品
• 英文别名: Calciate(3-), [N,N-bis[2-[bis(cboxymethyl) amino]ethyl]glycinato(5-)]-, trisodium; Pentetate Calcium Trisodium; calcium trisodium pentetate //BP; Calciate(3-), [N-[2-[bis[(cboxy-kO)Methyl]amino-kN]ethyl]-N-[2-[[(cboxy-kO)Methyl](cboxyMethyl)amino-kN]ethyl]glycinato(5-)-kN]-, sodiuM (1:3); Pentetate sodium calcium CRS; Calciate(3-), [N-[2-[bis[(cboxy-κO)methyl]amino-κN]ethyl]-N-[2-[[(cboxy-κO)methyl](cboxymethyl)amino-κN]ethyl]glycinato(5-)-κN]-, sodium (1:3); Pentetate sodium calcium; CALCIUMDTPA

物化性质

• 沸点: 721.1ºC at 760mmHg
• 分子式: C₁₄H₁₈CaN₃Na₃O₁₀
• 分子量: 497.35400
• 闪点: 389.9ºC
• 精确质量: 497.03100
• PSA: 182.71000
• 蒸汽压: 9.53E-23mmHg at 25°C
• 储存条件: 库房低温通风干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MB8210000 CHEMICAL NAME : Glycine, N,N-bis(2-(bis(carboxymethyl)amino)ethyl)-, calcium trisodium salt CAS REGISTRY NUMBER : 12111-24-9 LAST UPDATED : 199701 DATA ITEMS CITED : 13 MOLECULAR FORMULA : C14-H18-N3-O10.Ca.3Na MOLECULAR WEIGHT : 497.40 WISWESSER LINE NOTATION : OV1N1VO&2N1VO2N1VO&1VO &-NA- 3 &-CA- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2512 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 7269 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 659 mg/kg SEX/DURATION : female 9 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 1790 mg/kg SEX/DURATION : female 9-13 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - Central Nervous System TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2685 mg/kg SEX/DURATION : female 9-13 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - eye/ear TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 3581 mg/kg SEX/DURATION : female 7-11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 30 gm/kg SEX/DURATION : female 1-21 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 3580 mg/kg SEX/DURATION : female 7-11 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion TYPE OF TEST : DNA inhibition MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - rat Liver DOSE/DURATION : 10 mmol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,901,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9954 No. of Facilities: 116 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 1702 (estimated) No. of Female Employees: 1258 (estimated)