82454-61-3

• 常用中文名：5-炔吡啶-2-胺
• 常用英文名：5-Ethynylpyridin-2-amine
• CAS号：82454-61-3
• 分子式：C₇H₆N₂
• 分子量：118.136
• 发布时间：2018-02-23 08:00:00
• 更新时间：2024-01-05 22:41:41

名称

• 中文名: 5-乙炔吡啶-2-胺
• 英文名: 5-Ethynylpyridin-2-amine
• 英文别名: 5-ethynylpyridin-2-amine; 2-Pyridinamine, 5-ethynyl-; 5-Ethynyl-2-pyridinamine

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 246.5±25.0 °C at 760 mmHg
• 分子式: C₇H₆N₂
• 分子量: 118.136
• 闪点: 126.2±10.4 °C
• 精确质量: 118.053101
• PSA: 39.64000
• LogP: 0.80
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.594
• 储存条件: 2-8°C，避光，保存于惰性气体中

合成路线

457628-40-9 ~96% 82454-61-3

文献：Eisai RandD Management Co., Ltd. Patent: US2007/105904 A1, 2007 ; Location in patent: Page/Page column 74 ;

911114-11-9 ~89% 82454-61-3

文献：Hoffmann-La Roche Inc; Bachmann, Stephan; Bailey, Daniel; Brice, Jodie; Cedilote, Miall; Dong, Zhiming; Hildbrand, Stefan; Miller, Doreen; Spurr, Paul; Srivastava, Amit; Wichmann, Juergen; Woltering, Thomas; Yang, Jason; Zhang, Pingsheng Patent: US2013/85278 A1, 2013 ; Location in patent: Paragraph 0131; 0133 ;

1072-97-5 ~% 82454-61-3

文献：Matulenko, Mark A.; Paight, Ernest S.; Frey, Robin R.; Gomtsyan, Arthur; DiDomenico Jr., Stanley; Jiang, Meiqun; Lee, Chih-Hung; Stewart, Andrew O.; Yu, Haixia; Kohlhaas, Kathy L.; Alexander, Karen M.; McGaraughty, Steve; Mikusa, Joseph; Marsh, Kennan C.; Muchmore, Steven W.; Jakob, Clarissa L.; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Bhagwat, Shripad S. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 4 p. 1586 - 1605

141354-32-7 ~% 82454-61-3

文献：Matulenko, Mark A.; Paight, Ernest S.; Frey, Robin R.; Gomtsyan, Arthur; DiDomenico Jr., Stanley; Jiang, Meiqun; Lee, Chih-Hung; Stewart, Andrew O.; Yu, Haixia; Kohlhaas, Kathy L.; Alexander, Karen M.; McGaraughty, Steve; Mikusa, Joseph; Marsh, Kennan C.; Muchmore, Steven W.; Jakob, Clarissa L.; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Bhagwat, Shripad S. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 4 p. 1586 - 1605

926009-62-3 ~% 82454-61-3 926009-43-0

文献：Matulenko, Mark A.; Paight, Ernest S.; Frey, Robin R.; Gomtsyan, Arthur; DiDomenico Jr., Stanley; Jiang, Meiqun; Lee, Chih-Hung; Stewart, Andrew O.; Yu, Haixia; Kohlhaas, Kathy L.; Alexander, Karen M.; McGaraughty, Steve; Mikusa, Joseph; Marsh, Kennan C.; Muchmore, Steven W.; Jakob, Clarissa L.; Kowaluk, Elizabeth A.; Jarvis, Michael F.; Bhagwat, Shripad S. Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 4 p. 1586 - 1605

20511-12-0 ~% 82454-61-3

文献：Hoffmann-La Roche Inc; Bachmann, Stephan; Bailey, Daniel; Brice, Jodie; Cedilote, Miall; Dong, Zhiming; Hildbrand, Stefan; Miller, Doreen; Spurr, Paul; Srivastava, Amit; Wichmann, Juergen; Woltering, Thomas; Yang, Jason; Zhang, Pingsheng Patent: US2013/85278 A1, 2013 ;

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