622386-15-6

• 常用中文名：1-methylsulfonyl-4-[4-(2,2,2-trifluoroethoxy)phenyl]piperazine
• 常用英文名：1-methylsulfonyl-4-[4-(2,2,2-trifluoroethoxy)phenyl]piperazine
• CAS号：622386-15-6
• 分子式：C₁₃H₁₇F₃N₂O₃S
• 分子量：338.34600
• 发布时间：2016-10-22 15:22:03
• 更新时间：2024-01-09 15:57:02

名称

• 英文名: 1-methylsulfonyl-4-[4-(2,2,2-trifluoroethoxy)phenyl]piperazine
• 英文别名: 1-(methylsulfonyl)-4-[4-(2,2,2-trifluoroethoxy)phenyl]piperazine; Piperazine,1-(methylsulfonyl)-4-[4-(2,2,2-trifluoroethoxy)phenyl]

物化性质

• 分子式: C₁₃H₁₇F₃N₂O₃S
• 分子量: 338.34600
• 精确质量: 338.09100
• PSA: 58.23000
• LogP: 2.79300

合成路线

54533-09-4 57946-61-9 ~64% 622386-15-6

文献：Barta, Thomas E.; Becker, Daniel P.; Bedell, Louis J.; Boehm, Terri L.; Brown, David L.; Carroll, Jeffery N.; Chen, Yiyuan; Fobian, Yvette M.; Freskos, John N.; Gasiecki, Alan F.; Grapperhaus, Margaret L.; Heintz, Robert M.; Hockerman, Susan L.; Kassab, Darren J.; Khanna, Ish K.; Kolodziej, Stephen A.; Massa, Mark A.; McDonald, Joseph J.; Mischke, Brent V.; Mischke, Deborah A.; Mullins, Patrick B.; Nagy, Mark A.; Norton, Monica B.; Rico, Joseph G.; Schmidt, Michelle A.; Stehle, Nathan W.; Talley, John J.; Vernier, William F.; Villamil, Clara I.; Wang, Lijuan J.; Wynn, Thomas A. Patent: US2005/9838 A1, 2005 ; Location in patent: Page 113-114 ; US 20050009838 A1

823197-53-1 124-63-0 ~17% 622386-15-6

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2005/822 A1, 2005 ; Location in patent: Page/Page column 45 ; WO 2005/000822 A1