80791-93-1

• 常用中文名：5-碘-2'-氟-脱氧胞苷
• 常用英文名：5-Iodo-2'-fluoro-2'-deoxycytidine
• CAS号：80791-93-1
• 分子式：C₉H₁₁FIN₃O₄
• 分子量：371.104
• 发布时间：2017-09-30 01:25:47
• 更新时间：2026-07-11 16:25:29

名称

• 中文名: 5-碘-2'-氟-脱氧胞苷
• 英文名: 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one
• 中文别名: 4-氨基-1-((2R,3R,4R,5R)-3-氟-4-羟基-5-(羟基甲基)四氢呋喃-2-基)-5-碘嘧啶-2(1H)-酮
• 英文别名: 2''-DEOXY-2''-FLUORO-5-IODOCYTIDINE; Cytidine, 2'-deoxy-2'-fluoro-5-iodo; 5-iodo-2'-fluoroC; 4-AMINO-1-((3R,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)TETRAHYDROFURAN-2-YL)-5-IODOPYRIMIDIN-2(1H)-ONE; 4-Amino-1-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-iodopyrimidin-2(1H)-one; 5-iodo-2'-fluoro-2-deoxycytidine; 5-I-2'-F-dC; 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodo-1,2-dihydropyrimidin-2-one; 2'-Deoxy-2'-fluoro-5-iodocytidine

物化性质

• 密度: 2.4±0.1 g/cm3
• 沸点: 524.6±60.0 °C at 760 mmHg
• 分子式: C₉H₁₁FIN₃O₄
• 分子量: 371.104
• 闪点: 271.1±32.9 °C
• 精确质量: 370.977814
• PSA: 110.60000
• LogP: -0.27
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.791

合成路线

10212-20-1 ~38% 80791-93-1

文献：Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Tharnish, Phillip M.; McBrayer, Tamara R.; Stuyver, Lieven J.; Otto, Michael J.; Chu, Chung K.; Schinazi, Raymond F.; Watanabe, Kyoichi A. Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 5 p. 1641 - 1652

83966-99-8 ~% 80791-93-1

文献：Watanabe, Kyoichi A.; Su, Tsann-Long; Klein, Robert S.; Chu, Chung K.; Matsuda, Akira; et al. Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 152 - 156

31698-14-3 ~% 80791-93-1

文献：Shi, Junxing; Du, Jinfa; Ma, Tianwei; Pankiewicz, Krzysztof W.; Patterson, Steven E.; Hassan, Abdalla E. A.; Tharnish, Phillip M.; McBrayer, Tamara R.; Lostia, Stefania; Stuyver, Lieven J.; Watanabe, Kyoichi A.; Chu, Chung K.; Schinazi, Raymond F.; Otto, Michael J. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 875 - 879