93957-53-0

• 常用中文名：(3S,5R,E)-甲基 7-(3-(4-氟苯基)-1-异丙基-1H-吲哚-2-基)-3,5-二羟基庚-6-烯酸酯
• 常用英文名：Fluvastatin Methyl Ester
• CAS号：93957-53-0
• 分子式：C₂₅H₂₈FNO₄
• 分子量：425.49300
• 发布时间：2018-09-14 17:06:03
• 更新时间：2024-01-11 07:44:07
• Fluvastatin Methyl Ester is a precursor for Fluvastatin, which is a blocker of the liver enzyme HMG-CoA reductase.

名称

• 中文名: 氟伐他汀甲酯
• 英文名: Fluvastatin methyl ester
• 中文别名: (3R,5S,6E)-7-[3-(4-氟苯基)-1-(1-甲基乙基)-1-氢-吲哚-2-基]-3,5-二羟基庚-6-烯酸甲酯; [3R,5S-(E)]-7-[3-(4-氟苯基)-1-异丙基-1H-吲哚-2-基]-3,5-二羟基-6-庚烯酸叔丁酯
• 英文别名: methyl erythro-(E)-3,5-dihydroxy-7-[3-(4-fluorophenyl)-1-(1-methylethyl)indol-2-yl]hept-6-enoate; FLUVASTATIN MEHTYL ESTER; methyl (+/-)-erythro-(E)-7-[3'-(4''-fluorophenyl)-1'-(1''-methylethyl)indole-2'-yl]-3,5-dihydroxyhept-6-enoate; F4 TERT-BUTYL(E)-3,5-DIHYDROXY-7-[3-(4-FLUOROPHENYL)-1-METHYLETHYL-INDOL-2'-YL] HEPT-6-ENOATE; methyl (3r,5s,6e)-7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1h-indol-2-yl]-3,5-dihydroxy-6-heptenoate; (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester; [R*,S*-(E)]-(+/-)-7-[3-(4-Fluorophenyl)-1-(1-Methylethyl) -1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester; fluvastatin,methyl ester of; MFCD08458340

物化性质

• 密度: 1.18 g/cm3
• 沸点: 627.5ºC at 760 mmHg
• 分子式: C₂₅H₂₈FNO₄
• 分子量: 425.49300
• 闪点: 333.3ºC
• 精确质量: 425.20000
• PSA: 71.69000
• LogP: 4.71650
• 折射率: 1.568
• 储存条件: 2-8℃，密闭，干燥

合成路线

93957-52-9 ~% 93957-53-0

文献：Tetrahedron Letters, , vol. 28, # 2 p. 155 - 158

93957-52-9 ~% 93957-53-0 93957-53-0

文献：Tetrahedron Letters, , vol. 28, # 2 p. 155 - 158

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